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The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Not having enough cystatin M/E protein causes less hair growth and dry skin.

Innate lymphoid cells type 1 may contribute to alopecia areata by damaging hair follicles.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Epidermal stem cells help renew skin and regenerate hair follicles.

Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.

Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.

Removing HIF-P4H-2 from certain skin cells in mice causes hair loss on the body but not the head.

Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.

Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Stem cell niches support, regulate, and coordinate stem cell functions.

Cannabinoids may help treat various skin conditions.

Dermal adipose tissue in mice can change and revert to help with skin health.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Vitamin D and calcium are important for skin stem cell function and wound healing.

Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.

The circadian clock in skin cells controls their growth and rest cycles.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.

Glucosylceramides are essential for healthy skin and proper wound healing.