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The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

YAP and TAZ are crucial for skin cell growth and repair.

Adipokines affect skin health and could be targeted for treating skin diseases.

Different types of skin fibroblasts have unique roles in skin health and disease.

Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.

Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.

Autophagy helps mouse glands stay healthy, prevents early aging, and maintains their oil and scent production.

Autophagy helps delay aging in mouse glands, maintains fat balance, and controls scent production.

Certain genes related to sulfur metabolism are more active during the growth phase of Cashmere goat wool, and melatonin might help this process.

Mammary stem cells drive mammary gland growth by branching and cell mixing.

TREM2 macrophages and unsaturated lipids contribute to acne inflammation.

PEODDN is a rare skin disorder with limited treatment options, best treated with laser therapy.

Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.

Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.

Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.