Search

for
Search:

GlossaryHair Growth Cycle (hair cycle progression)

process where hair follicles undergo growth, transition, and rest phases

The Hair Growth Cycle, also known as Hair Follicle Cycling, consists of three main phases: anagen (growth phase), catagen (transitional phase), and telogen (resting phase). During the anagen phase, hair actively grows from the follicle, which can last several years. The catagen phase is a short period where growth stops, and the hair follicle shrinks. Finally, in the telogen phase, the hair rests before eventually falling out, making way for new hair to begin the cycle again. Understanding these phases is crucial for diagnosing and treating hair loss conditions like alopecia.

Related Terms

Sort by

Research

30 / 1000+ results

Defining the Molecular Signature of the Hair Follicle Dermal Sheath and Its Functional Requirement for Hair Cycle Progression During Catagen

research Defining the Molecular Signature of the Hair Follicle Dermal Sheath and Its Functional Requirement for Hair Cycle Progression During Catagen

April 2017 in “Journal of Investigative Dermatology”

The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

research Procyanidin B-2 Extracted from Apples Promotes Hair Growth: A Laboratory Study

37 citations, January 2002 in “British journal of dermatology/British journal of dermatology, Supplement”

Apple extract called procyanidin B-2 was found to greatly increase hair growth.

research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation

321 citations, January 2012 in “Cell stem cell”

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

research Gasdermin A3-Mediated Cell Death Causes Niche Collapse and Precocious Activation of Hair Follicle Stem Cells

2 citations, April 2019 in “Journal of Investigative Dermatology”

Gasdermin A3 causes hair follicle stem cells to activate too early, leading to hair loss.

research Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression

25 citations, July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.

research Iron Deficiency and Diffuse Nonscarring Scalp Alopecia in Women: More Pieces to the Puzzle

30 citations, October 2010 in “Journal of The American Academy of Dermatology”

The conclusion suggests a possible link between iron levels and hair health in women, recommending further research on iron supplementation for hair loss.

research Investigating the Role of Mef2c in Hair Follicle Cycling

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

MEF2C is crucial for normal hair cycle progression.

research SIRT7 Activates Quiescent Hair Follicle Stem Cells to Ensure Hair Growth in Mice

38 citations, July 2020 in “EMBO journal”

SIRT7 protein is crucial for starting hair growth in mice.

research Lactate Dehydrogenase Activity Drives Hair Follicle Stem Cell Activation

202 citations, August 2017 in “Nature cell biology”

Lactate production is important for activating hair growth stem cells.

research Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair

314 citations, April 2010 in “Developmental Cell”

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

research Epidermal Abnormalities and Increased Malignancy of Skin Tumors in Human Epidermal Keratin 8-Expressing Transgenic Mice

49 citations, August 2004 in “The FASEB Journal”

Mice with human skin protein K8 had more skin problems and cancer.

research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but Not for Maintenance of the Epidermal Stem Cell Compartment

25 citations, March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.

research Clock Genes, Hair Growth, and Aging

55 citations, March 2010 in “Aging”

Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.

research Hair Growth Promoting Effect of 4HGF Encapsulated with PGA Nanoparticles by β-Catenin Activation and Related Cell Cycle Molecules

7 citations, July 2019 in “International Journal of Molecular Sciences”

PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.

Bacillus/Trapa Japonica Fruit Extract Ferment Filtrate Enhances Human Hair Follicle Dermal Papilla Cell Proliferation via the Akt/ERK/GSK-3β Signaling Pathway

research Bacillus/Trapa Japonica Fruit Extract Ferment Filtrate Enhances Human Hair Follicle Dermal Papilla Cell Proliferation via the Akt/ERK/GSK-3β Signaling Pathway

10 citations, May 2019 in “BMC Complementary and Alternative Medicine”

The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.

Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix

research Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix

30 citations, April 2017 in “European Journal of Cell Biology”

CIP/KIP proteins help stop cell division and support hair growth.

research Local Circadian Clock Gates Cell Cycle Progression of Transient Amplifying Cells During Regenerative Hair Cycling

116 citations, May 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

research Does Low-Energy Fractional Carbon Dioxide Laser Therapy Improve Hair Regrowth in Female-Pattern Hair Loss?

September 2024 in “Egyptian Journal of Dermatology and Venerology”

Low-energy fractional CO2 laser therapy significantly improves hair regrowth in women with female-pattern hair loss.

research Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways

73 citations, November 2000 in “Proceedings of the National Academy of Sciences of the United States of America”

There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.

research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis

61 citations, January 2011 in “PloS one”

Notch signaling is essential for healthy skin and hair follicle maintenance.

research Potential of Polar Lipids from Bovine Milk to Regulate the Rodent Dorsal Hair Cycle

7 citations, June 2012 in “Journal of dairy science”

Bovine milk fats applied to mouse skin can promote hair growth similar to known hair growth treatments.

research Telogen Elongation in the Hair Cycle of ob/ob Mice

5 citations, August 2015 in “Bioscience, Biotechnology, and Biochemistry”

Obese mice with a leptin gene mutation have a longer resting phase in their hair cycle, which may help understand certain hair loss conditions.

research Gab1 and MAPK Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence

36 citations, October 2015 in “Cell reports”

Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.

research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche

6 citations, May 2013 in “PloS one”

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

research CXCL12 Inhibits Hair Growth Through CXCR4

April 2022 in “Biomedicine & Pharmacotherapy”

CXCL12 protein slows down hair growth through its receptor CXCR4. Blocking this can potentially increase hair growth.

research XMU-MP-1 Induces Growth Arrest in a Model Human Mini-Organ and Antagonizes Cell Cycle-Dependent Paclitaxel Cytotoxicity

4 citations, September 2020 in “Cell division”

XMU-MP-1 stops cell growth in a human mini-organ and reduces the effectiveness of the chemotherapy drug paclitaxel.