Does Low-Energy Fractional Carbon Dioxide Laser Therapy Improve Hair Regrowth in Female-Pattern Hair Loss?

    Abeer Attia Tawfik, Noha Gahdan, Moataz Nosseir
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    TLDR Low-energy fractional CO2 laser therapy significantly improves hair regrowth in women with female-pattern hair loss.
    The study on 30 female patients with female-pattern hair loss (FPHL) found that low-energy fractional CO2 laser therapy significantly improved hair regrowth, evidenced by increased terminal hair count, hair thickness, and density, and decreased vellus hair count, with P values of 0.001. The control area treated with saline showed no significant changes. Minimal side effects were reported, and 70% of patients were satisfied with the results. The therapy likely works by stimulating stem cell populations and promoting hair follicle cycle progression through the Wnt/β-catenin signaling pathway, suggesting it as a promising treatment for FPHL.
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