Transepidermal Delivery of Triamcinolone Acetonide or Platelet Rich Plasma Using Either Fractional Carbon Dioxide Laser or Microneedling in Treatment of Alopecia Areata

October 2022 in “ Dermatology practical & conceptual ”

Khaled El Mulla, Eman Elmorsy, Dalia Halwag, Eman Hassan

triamcinolone acetonide platelet-rich plasma fractional carbon dioxide laser microneedling alopecia areata hair regrowth PRP fractional CO2 laser

From the encyclopedia

Triamcinolone Acetonide →

Platelet-Rich Plasma →

growth factors taken from your blood and injected into your scalp to stimulate hair

Microneedling →

technique to create small wounds in skin to activate collagen production and hair growth

Studysummary This study found that micro-needling with triamcinolone acetonide led to the best treatment outcomes for alopecia areata compared to other methods of trans-epidermal drug delivery.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

13 / 13 results

research Evaluation of Platelet-Rich Plasma vs Intralesional Steroid in Treatment of Alopecia Areata

19 citations , May 2019 in “Journal of Cosmetic Dermatology”

In this study, both platelet-rich plasma and intralesional corticosteroids improved hair re-growth in alopecia areata patients, but the difference between treatments was not significant, with fewer relapses observed in the platelet-rich plasma group.

research Laser-Assisted Drug Delivery for the Treatment of Androgenetic Alopecia: Ablative Laser Fractional Photothermolysis to Enhance Cutaneous Topical Delivery of Platelet-Rich Plasma — With or Without Concurrent Bimatoprost and/or Minoxidil

9 citations , January 2019 in “Dermatology Online Journal”

In this study, researchers suggest that laser-assisted drug delivery could enhance the administration of platelet-rich plasma, and potentially bimatoprost or minoxidil, for patients with androgenetic alopecia by ensuring uniform placement in the dermis without injection pain.

research Platelet-Rich Plasma Versus Minoxidil 5% in Treatment of Alopecia Areata: A Trichoscopic Evaluation

62 citations , October 2016 in “Dermatologic Therapy”

This study found that platelet-rich plasma was more effective for treating alopecia areata than topical 5% minoxidil, leading to earlier hair regrowth and reduction in hair abnormalities.

research Applications of Platelet-Rich Plasma in Dermatology: A Critical Appraisal of the Literature

79 citations , October 2015 in “Journal of Dermatological Treatment”

This review assesses the use of platelet-rich plasma in dermatology and concludes that while there may be modest benefits for certain conditions, more evidence is needed before it can be widely recommended.

research Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias

58 citations , January 2015 in “International Journal of Trichology”

This review evaluates the therapeutic potential of platelet-rich plasma for treating non-cicatricial alopecias and suggests it may be effective, though further research is needed to confirm its efficacy.

research Transepidermal Drug Delivery: A New Treatment Option for Areata Alopecia?

40 citations , September 2014 in “Journal of cosmetic and laser therapy”

This case series found that combining ablative fractional resurfacing and acoustic pressure ultrasound with triamcinolone treatment led to complete recovery in patients with areata alopecia.

research Alopecia Areata: Successful Outcome with Microneedling and Triamcinolone Acetonide

53 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Microneedling combined with triamcinolone can safely stimulate faster hair regrowth in people with Alopecia Areata.

research Hair Shafts in Trichoscopy

86 citations , October 2013 in “Dermatologic Clinics”

Trichoscopy is a useful non-invasive method for diagnosing different hair loss conditions.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations , April 2013 in “British Journal of Dermatology”

In this study, platelet-rich plasma significantly increased hair regrowth and reduced symptoms of alopecia areata compared to triamcinolone acetonide or placebo, with no observed side effects.

research Dermoscopic Evaluation of Therapeutic Response to an Intralesional Corticosteroid in the Treatment of Alopecia Areata

35 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

This study found that intralesional triamcinolone acetonide is effective for treating localized patchy alopecia areata, with dermoscopy aiding in early detection of clinical response and adverse effects.

research Hair and Scalp Dermatoscopy

245 citations , March 2012 in “Journal of The American Academy of Dermatology”

This review discusses the dermoscopic features of common hair and scalp disorders and reports no new clinical results, aiming to assist dermatologists in diagnosing conditions like tinea capitis and alopecia areata.

research Clinical Significance of Dermoscopy in Alopecia Areata: Analysis of 300 Cases

196 citations , June 2008 in “International Journal of Dermatology”

This study found that dermoscopic indicators like black dots and tapering hairs are valuable markers for diagnosing and assessing the severity and activity of alopecia areata in Asian patients.

research Efficacy And Safety Of A New Clobetasol Propionate 0.05% Foam In Alopecia Areata: A Randomized, Double-Blind Placebo-Controlled Trial

114 citations , October 2006 in “Journal of the European Academy of Dermatology and Venereology”

In this study, clobetasol propionate foam demonstrated effectiveness and good patient compliance as a safe topical treatment for moderate to severe alopecia areata, with significant hair regrowth compared to placebo.