research Large-Scale Multicenter Prospective Registry Study of Ripretinib in Advanced GIST: A Real-World Study from China
Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.
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research Sexual Dysfunction, Including Hypoactive Sexual Desire Disorder: Diagnosis and Treatment Recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research Pyodermatitis Vegetans Associated with Multiple Myeloma
A skin condition called pyodermatitis vegetans was found in a patient with multiple myeloma for the first time.
research Androgen Replacement Therapy in Women
Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
research Clinical Evaluation of Women Presenting with Low Libido and Determination of Whether Androgen Therapy Might Be Appropriate
Androgen therapy might help some women with low libido, but it has risks and should be used carefully.
research Polyglandular Syndrome Type 1 Complicated with Dilated Cardiomyopathy: A Case Report
A 27-year-old with APS-1 showed improvement in symptoms after treatment.
research Fibroblast Heterogeneity and Functions: Insights from Single-Cell Sequencing in Wound Healing, Breast Cancer, Ovarian Cancer, and Melanoma
Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
research The Ecology of Human Sleep Project: Protocol for a Longitudinal Cohort Repeated-Measurement-Burst Study to Assess the Relationship Between Sleep Determinants and Sleep Outcomes Under Real-World Conditions Across Time of Year
The study aims to understand how mood, physical activity, light exposure, and seasonal changes affect sleep patterns.
research Skin Challenges in COVID-19 Pandemic: The Importance of Cosmeceuticals
Cosmeceuticals are important for managing skin issues during the COVID-19 pandemic.
research Medical Care for Children and Adolescents with Gender Dysphoria and Gender Inconsistency in Light of Current Recommendations: How to Implement the 'Primum Non Nocere' Principle?
The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.
research Myotonic Dystrophy Type 1: Enhancing Patient Management Through Genetic and Multisystem Studies
There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.
research The Dark Side of the Language: Pre-Trained Transformers in the DarkNet
Pre-trained Transformers need extreme retraining to perform well on DarkNet data.
research Case Report: Disorder of Sex Development 46, XY with Proximal Hypospadias in a 10-Year-Old Twin Boy
A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.
research Type 3 Autoimmune Polyendocrine Syndrome Diagnosed in an 87-Year-Old Patient with Concomitant Chronic Autoimmune Urticaria
An 87-year-old woman was diagnosed with type 3 autoimmune polyendocrine syndrome and had multiple autoimmune issues.
research Overview and Future of Hemocomponents and Natural Guided Regeneration
The document concludes that more standardized research is needed to fully understand and optimize the use of platelet-rich fibrin in regenerative medicine.
research Abstracts from the 17th Congress of the European Society for Dermatology and Psychiatry
The congress showed that psychological therapy can help skin condition patients, social media affects acne stigma, education improves atopic dermatitis, and patient satisfaction in dermatology is high, especially with good doctor engagement.
research Female Sexual Dysfunction: Prevalence, Causes, and Treatments
Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.
research Book Review
The book is highly praised as an essential resource for plastic surgeons, despite minor gaps.
research A Comprehensive Review of Microneedling as a Potential Treatment Option for Androgenetic Alopecia
research Psoriasiform Skin Reaction Due to Brazilian Keratin Treatment
Brazilian Keratin Treatment can cause skin reactions like redness and scaling, possibly due to formaldehyde.
research Scalp Biophysical Characteristics in Males with Androgenetic Alopecia: A Comparative Study with Healthy Controls
Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.
research Hormonal and Genetic Etiology of Male Androgenetic Alopecia
research Exploiting Recent Trends in the Treatment of Androgenic Alopecia Through Topical Nanocarriers of Minoxidil
research Androgenetic Alopecia: What Impact Does It Have on the Quality of Life?
Androgenetic Alopecia (AGA) greatly lowers quality of life, causing stress and low self-esteem, with those seeking treatment experiencing more impairment.
research Dermoscopy of Cutaneous Adnexal Tumors: A Systematic Review of the Literature
Most cutaneous adnexal tumors examined were benign and resembled common skin tumors.
research Prioritizing Susceptibility Genes for the Prognosis of Male-Pattern Baldness With Transcriptome-Wide Association Study
Identified genes linked to male-pattern baldness may help develop new treatments.
research Molecular Genetics of the PI3K-AKT-mTOR Pathway in Genodermatoses: Diagnostic Implications and Treatment Opportunities
The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.
research Update on Hidradenitis Suppurativa: Connecting the Tracts
The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.
research Epigenetic Age Estimation in Saliva and Buccal Cells
The model accurately predicts age from saliva and buccal cells for forensic use.