4 citations
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August 2024 in “Journal of Cosmetic Dermatology” This study reports that injecting a non-cross-linked hyaluronic acid compound into keratosis pilaris-affected skin led to significant improvements in roughness, redness, and overall skin condition, while maintaining a favorable safety profile, making it a promising alternative treatment option.
4 citations
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March 2017 in “Revista del Hospital Italiano de Buenos Aires” This review discusses polycystic ovary syndrome, its diagnosis criteria, and treatment options, including weight loss and medications, but reports no new clinical results.
4 citations
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May 1981 in “Australian Journal of Biological Sciences” This study observed that rat dermal tissue cultures, rich in hair follicle cells, produce various glycosaminoglycans, including hyaluronic acid and dermatan sulfate, which change in synthesis and sulfation patterns over time.
4 citations
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October 2022 in “Aesthetic surgery journal” This study reports that percutaneous superficial temporal arterial hyaluronidase injection effectively treated necrosis of the frontotemporal skin and ipsilateral scalp, with patients experiencing significant recovery in skin appearance and hair regrowth 2 to 3 months after injection, following complications from hyaluronic acid filler.
3 citations
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April 2025 in “Advanced Healthcare Materials” In this study, researchers developed hyaluronic acid derivatives functionalized with nitric oxide photodonors for light-activated skin treatments, finding that the compounds released NO under blue light and enhanced keratinocyte proliferation and migration, suggesting potential for therapeutic use.
3 citations
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July 2023 in “International Journal of Biological Macromolecules” In this study, the researchers developed a hydrogel mimicking the fetal environment that significantly accelerated wound healing and hair follicle regeneration in vivo, with over 94% wound closure in 14 days, surpassing hydrogels lacking certain additives.
3 citations
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November 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review evaluated existing studies on platelet-rich plasma for facial rejuvenation and found limited clinical evidence supporting its effectiveness, suggesting that more research is needed to establish its utility.
3 citations
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September 2018 in “Journal of Biomaterials Science, Polymer Edition” This study found that pyramidal neural precursors best grew neurites on matrigel, while neural stem cells differentiated directionally on aligned fibrin, suggesting the importance of biomaterial selection for cell culture.
3 citations
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June 1979 in “The Journal of Dermatology” This study found that the dermal glycosaminoglycan content and mast cell count in rats peaked during the anagen stage of hair growth and decreased during later stages.
3 citations
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November 2022 in “Facial plastic surgery & aesthetic medicine” In this study, researchers introduced an ultrasound-guided technique for injecting hyaluronic acid fillers into the temple area to enhance safety and precision by visualizing filler placement in the interfascial space.
2 citations
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March 2021 in “Pakistan veterinary journal” This study found that injecting hyaluronic acid fillers using a layered feathering technique temporarily corrected entropion and relieved associated symptoms in two dogs, an Old English Bulldog and a Chow Chow, maintaining eyelid positions for 6-8 months.
2 citations
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January 2019 in “Biomecánica” This review examines the roles of Hyaluronic Acid and Versican in the skin extracellular matrix and reports no new research findings, highlighting their involvement in processes like differentiation and wound healing.
2 citations
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December 1994 in “International Journal of Cosmetic Science” In this study, the combination of biologically engineered hyaluronic acid and polyquaternium-10 improved hyaluronic acid's retention and moisturizing effects on hair by forming a stable complex that increased binding affinity to keratin.
1 citations
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September 2025 in “Journal of Ultrasound in Medicine” This study found that AI using YOLOv11 architecture can reliably differentiate between hyaluronic acid and silicone oil cosmetic fillers on ultrasound, achieving high accuracy, whereas identifying calcium hydroxyapatite and polymethylmethacrylate remains less consistent, requiring further improvements.
1 citations
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April 2025 in “Journal of Applied Polymer Science” This study found that microneedles based on polyphosphazene with green tea polyphenols significantly enhanced wound healing in a diabetic rat model.
1 citations
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July 2023 in “International Journal of Biological Macromolecules” In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.
1 citations
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July 2023 in “Pharmaceutics” In this study, researchers developed grooved microneedles made from hyaluronic acid for precise transdermal drug delivery, achieving accurate dosage with a high probability of delivery (98% or more) by using an easy-to-operate applicator for shearing force.
1 citations
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June 2023 in “Chemical engineering journal” In this laboratory study, a novel minoxidil-loaded microneedle patch demonstrated potential for treating alopecia areata by promoting slow drug release and reducing application frequency, while exhibiting antibacterial properties to prevent infection during use.
1 citations
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November 2022 in “Molecules/Molecules online/Molecules annual” This study found that low-molecular-weight hyaluronate significantly improved the mechanical strength and elastic modulus of overbleached hair by enhancing hydrogen bond networks within keratin.
1 citations
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December 2021 in “Journal of drugs in dermatology” In this double-blind study, a novel hyaluronic acid gel for lip augmentation was found to be as effective and safe as a commercially available gel, with similar adverse event profiles and high patient and investigator improvement ratings over six months.
1 citations
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October 2021 in “Bioactive compounds in health and disease” This study found that anthocyanins from Hibiscus rosa-sinensis petals reduced oxidative stress and increased antioxidant enzyme activity in the livers of streptozotocin-induced diabetic rats.
1 citations
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January 2020 in “Инфекционные болезни. Новости, мнения, обучение” This article reviews the role of vitamin D in regulating immune responses related to autoimmune diseases like alopecia areata, but it presents no new clinical findings.
1 citations
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January 2015 in “ADMET and DMPK” This study observed that hyaluronan's transformation into HA·3Ca and its hydrate increases drug absorption by changing its molecular characteristics, influenced by zwitterionic character and acidic pH.
1 citations
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October 2025 in “Nano Research” In this study, researchers developed a dissolvable microneedle patch combining HA-TEMPO and Portulaca oleracea L.-derived nanoparticles, which effectively reduced oxidative stress and inflammation in an atopic dermatitis model while restoring immune balance, suggesting a promising treatment strategy.
September 2025 in “Editora Pasteur eBooks” This abstract discusses the broad scope of dermatology and aesthetic procedures, highlighting their significant multidisciplinary evolution within the health sciences, but it does not report specific study results.
August 2025 in “Journal of Medical and Biological Engineering” In this study, a needle-free supersonic atomizer delivering Bacopa monnieri extract with hyaluronan was found to enhance hair growth in mice more effectively than the traditional smear method and minoxidil.
July 2025 in “Journal of Cosmetic and Laser Therapy” This case study reported rare alopecia resulting from a hyaluronic acid filler injection, noting approximately 80% hair regrowth after treatment with topical minoxidil.
June 2025 in “Problems of Cryobiology and Cryomedicine” In this study, the researchers found that tyndallization effectively sterilizes aqueous solutions of hyaluronic acid without diminishing their regenerative properties, and these properties remain intact even at low temperatures, supporting potential applications in cryobiology and cryomedicine.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” This study presented a case where a 23-year-old woman with alopecia induced by hyaluronic acid injections experienced full hair regrowth using a combination of Concentrated Growth Factor, microneedling, and minoxidil, and also reviewed literature noting variable success rates with other treatments.
April 2025 in “Journal of Cosmetic Dermatology” Combining radiofrequency and ultrasound significantly boosts skin's natural hyaluronic acid production.