Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identified a genetic locus associated with coat type in domestic dogs, showing certain variants linked to single-coated breeds and suggesting potential regulatory roles.

This review highlights recent genetic research advancements in understanding hereditary hair diseases but reports no new study results, emphasizing the identification of genes related to both monogenic and polygenic hair disorders.

DNA can predict physical traits like eye and hair color accurately, especially in Europeans, but predicting other traits and in diverse populations needs more research.

This study found no significant genetic correlations between male pattern baldness and COVID-19 outcomes, suggesting that shared genetic factors may not explain the reported association.

In this study, researchers conducting a genome-wide association study on 263 adult female goats identified significant genomic variants linked to coarse hair diameter, particularly emphasizing a crucial region on Chromosome 10. These findings enhance understanding of the genetic factors influencing fiber diameter in goats.

This study found that among Large White × Min pigs, 15 significant copy number variation regions were associated with villi hair traits, and identified candidate genes potentially linked to cold resistance, suggesting implications for breeding cold-resistant pigs.

This research discusses the complex immune pathogenesis of alopecia areata and highlights the success of Jak inhibitors and IL-4Rα antagonists, while IL-17A and PDE4 inhibitors showed limited efficacy; controlled trials are advocated to better understand cytokine involvement.

This genome-wide association study identified several genetic markers, including specific SNPs and HLA genotypes, associated with alopecia areata susceptibility in the Taiwanese population, highlighting key pathways involved in immune response and offering insights into the genetic origins of this autoimmune condition.

This chapter discusses genetic polymorphisms related to phenotypes that differentiate between populations and reports no new results; it highlights the role of DNA technology in understanding human adaptation history.

This review discusses genetic and epigenetic studies of PCOS, highlighting Genome-Wide Association Studies that found genetic variants related to gonadotrophin secretion influencing PCOS susceptibility, but it reports no new findings.

This study found no strong genetic link between hair color and alopecia areata risk, although a weak inverse association with blond hair was suggested, noting the results are exploratory and require further investigation with larger cohorts.

In this study, researchers identified 19 genetic risk loci and highlighted 16 candidate causal genes, including immune-related ones, associated with polycystic ovary syndrome, emphasizing the role of specific immune cells like T cells and NK cells in its pathogenesis.

This review summarizes the application of genome wide association studies and selection signature analyses in sheep and goat breeding in China, highlighting genomic regions that influence traits like reproductive performance and body size.

This review examines the genetics of acne vulgaris, concluding that stem/progenitor cell maintenance and cellular migration are key processes in its pathogenesis, potentially shifting future treatment strategies beyond traditional antibiotics and retinoids, which have notable side effects.

This study found that genetic predictions of male pattern baldness from European populations do not generalize well to African populations, highlighting significant differences in genetic architecture between them.

This study identified 193 plasma proteins associated with prostate cancer risk, validating 20 high-risk proteins including KLK3, and pinpointed potential drug targets like HSPB1, RRM2B, and PSCA through genetic analysis, offering new insights for biomarkers and treatments.

In this study using Mendelian randomization analysis, researchers found no causal relationship between androgenic alopecia and prostate cancer risk, suggesting that previously observed associations in epidemiological studies might not be causal.

This study suggests that valine and certain VLDL subfractions are positively associated with androgenetic alopecia risk, while reverse analysis showed AGA does not affect these metabolites.

In this study, a bidirectional Mendelian randomization analysis found a causal link between alopecia areata and hypothyroidism, indicating that each condition may influence the other, while no similar relationship was observed between androgenetic alopecia and hypothyroidism.

This study found that genetic predictions of male pattern baldness derived from European data do not accurately predict baldness in African populations, highlighting significant continental differences in genetic architecture and evolutionary history.

This study offers evidence suggesting a probable causal role of certain gut microbiota in the development of alopecia areata.

This study found that nociplastic type pain is a complex and heritable trait, with significant genetic overlap with multisite chronic pain and some connection to rheumatoid arthritis and a neuropathic pain phenotype.

This study in Japanese women identified SNP rs2419385 as significantly associated with hair thinning, suggesting potential involvement of nearby genes in its development.

This study found shared genetic pathways linking acne with multiple mental health disorders and observed a potential causal relationship between acne and increased depression risk.

Men can have genetic risks for PCOS-related traits like obesity and diabetes.

This thesis analyzed four skin aging features and their relationships with lifestyle, physiological factors, and genetics.

This study identified putative causal mutations for PCOS among first-degree relatives, although functional analysis of a specific GDF9 mutation was unsuccessful.

This review discusses the genetic and molecular factors involved in human hair follicle development and cycling, highlighting identified genes and pathways associated with hair diseases but reports no new results.

Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.

Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.