45 citations
,
November 2012 This review discusses the association between androgen receptor gene polymorphism and PCOS, reporting mixed findings on whether shorter or longer CAG repeats are linked to the disorder; it provides no new results and calls for further studies.
41 citations
,
April 2006 in “Hormone and metabolic research” This abstract lists key topics related to non-genomic steroid effects and protein interactions, but reports no new research findings.
40 citations
,
May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.
36 citations
,
October 2014 in “Langmuir” This study concluded that bleach treatment partly transforms the hydrophobic top layer of human hair cuticles into a hydrophilic surface with clustered cysteic acid, visualized at the nano-scale using dynamic Chemical Force Microscopy.
33 citations
,
January 2000 in “Acta Oto-Laryngologica” In this study, epidermal growth factor (EGF) was shown to increase the length of rat organ of Corti segments containing supernumerary hair cells, with the effect peaking at birth and independent of cell division.
28 citations
,
December 2010 in “Langmuir” Hair fibers interact through classical forces, which are influenced by treatments and products, important for hair care and other applications.
14 citations
,
November 2021 in “Nanoscale” This study's simulations revealed the complex "onion-like" organization of a lipid nanoemulsion droplet containing vitamins A and E for skin delivery, showing distinct concentration patterns of these vitamins within different layers of the nanodroplet.
13 citations
,
May 2007 in “Journal of Endocrinology” This study found that A-ring reduced derivatives of norethisterone and levonorgestrel exhibit estrogen-like potency in rat osteoblasts, suggesting a mechanism for 19-norprogestins' bone restoration effects in postmenopausal women.
12 citations
,
April 2023 in “Molecular Pharmaceutics” This study demonstrated that a microarray patch can deliver antibodies in a controlled and prolonged manner, maintaining their functionality after manufacturing and heat exposure, with successful pharmacokinetic proof-of-concept in rats.
9 citations
,
January 2018 in “Journal of the European Academy of Dermatology and Venereology” A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.
9 citations
,
November 2006 in “Journal of Microscopy” This study using an apertureless scanning near-field optical microscope found that dye restricted to hair's periphery remains mainly on the surface and in the endocuticle.
8 citations
,
November 2020 in “Journal of Cosmetic Dermatology” This preclinical study observed that a nanoencapsulated ingredient complex, AcPi, may prevent hair follicle aging and hair loss by reducing oxidative stress, enhancing mitochondrial activity and WNT/β-catenin signaling, and controlling androgenic metabolism when tested on human scalp cultures.
7 citations
,
December 2020 in “Dermatologic Therapy” In this study, intradermal injections of 0.5% minoxidil significantly improved hair growth and volume in women with female androgenetic alopecia compared to a placebo, with a good safety profile reported.
6 citations
,
November 2020 in “Molecular and Cellular Endocrinology” This study found that androgens downregulate BMP2 in dermal papilla cells, inhibiting hair follicle stem cell differentiation, while BMP2 addition may restore hair lineage differentiation through the Wnt/β-catenin pathway.
6 citations
,
March 2020 in “Anais Brasileiros de Dermatologia” This report highlights the successful treatment of skin and nail manifestations in a patient with primary hypothyroidism using levothyroxine, emphasizing the role of cutaneous symptoms in identifying thyroid disease.
6 citations
,
June 2016 in “The anatomical record” This study found that Merkel cells in dogs are most numerous in sensory receptive areas like oral mucosa and facial skin, indicating a potential role in tactile sensation.
5 citations
,
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that in adult mice, a cell-autonomous size control mechanism involving the RB pathway determines the timing of S phase entry in epidermal stem cells based on their size, while external microenvironment factors influence growth rates but not this intrinsic coupling.
5 citations
,
March 2012 in “Veterinary dermatology” This case report describes a potential drug-induced localized scleroderma in a Persian cat following the application of a 'spot-on' treatment.
4 citations
,
November 2015 in “Research Journal of Medicinal Plant” This study found that ethanolic, aqueous, and hydroethanolic extracts of Tridax procumbens inhibited mitosis and caused mutagenic effects on cell division in Allium cepa root meristematic cells.
4 citations
,
July 2015 in “Veterinary Dermatology” This study identified the expression of 5αR1 and 5αR3 enzymes in canine skin, which may advance understanding and treatment of alopecia X.
3 citations
,
April 2025 in “Nature Communications” This study concluded that the GIANT brain atlas, which integrates genetic and neuroanatomical variations, provides a more accurate representation of brain structure than traditional neuroanatomical atlases, allowing for better exploration of genetic influences on the brain.
3 citations
,
September 2024 in “Frontiers in Bioscience-Scholar” This study reported that Pantaneiro sheep from the Pantanal region of Brazil exhibit greater genetic variability and adaptability compared to the commercial Texel breed, highlighting their potential for further research and importance in Brazilian sheep farming.
2 citations
,
April 2025 in “BMC Infectious Diseases” According to this study, nearly one-third of the participants experienced Long COVID, highlighting ongoing concerns about the disease's long-term implications despite the pandemic being under control.
2 citations
,
February 2024 in “Journal of the European Academy of Dermatology and Venereology” Diffuse alopecia areata in children has unique features and needs specific treatment.
2 citations
,
July 2022 in “Journal of the Endocrine Society” This study identified several rare genetic variants related to insulin resistance in women with PCOS, highlighting the potential for monogenic conditions in patients with extreme or atypical phenotypes.
2 citations
,
June 2022 in “Scientific reports” This study found that women with PCOS had significantly higher hair cortisol concentrations, suggesting hyperactivation of the HPA axis may affect metabolic and inflammatory markers in those with elevated cortisol levels.
2 citations
,
January 2017 Hair movement can indicate hair quality and health.
2 citations
,
November 2009 in “DSpace (Federal University of Santa Catarina)” Brunfelsia uniflora has good antioxidant properties and moderate antibacterial activity.
2 citations
,
January 2006 in “Publicatio UEPG Ciencias Biologicas e da Saude” This review discusses the potential of dental stem cells from deciduous and permanent teeth for tissue regeneration and reports no new experimental results.
1 citations
,
October 2025 in “Nature Communications” This study observed that, in mouse ear epidermal stem cells, a cell-autonomous size control mechanism involving the RB pathway dictates S phase entry timing based on cell size, despite external environmental variations affecting growth rates.