The Effects of Synthetic 19-Norprogestins on Osteoblastic Cell Function Are Mediated by Their Non-Phenolic Reduced Metabolites

    May 2007 in “ Journal of Endocrinology ”
    Juana Enríquez, Ana E. Lemus, Jesús Chimal‐Monroy, Higinio Arzate, Gustavo A. García, Bertha Herrero, Fernando Larrea, Gregorio Pérez‐Palacios
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    Studysummary This study found that A-ring reduced derivatives of norethisterone and levonorgestrel exhibit estrogen-like potency in rat osteoblasts, suggesting a mechanism for 19-norprogestins' bone restoration effects in postmenopausal women.
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