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research The effects of synthetic 19-norprogestins on osteoblastic cell function are mediated by their non-phenolic reduced metabolites

13 citations , May 2007 in “Journal of Endocrinology”

This study found that A-ring reduced derivatives of norethisterone and levonorgestrel exhibit estrogen-like potency in rat osteoblasts, suggesting a mechanism for 19-norprogestins' bone restoration effects in postmenopausal women.

research Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1

12 citations , June 2001 in “Bioorganic & Medicinal Chemistry”

This study found that octahydrobenzo[c]quinolizin-3-one derivatives, particularly compound 3, were potent and selective inhibitors of the enzyme 5α-reductase type 1.

Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors

research Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor.

23 citations , January 2001 in “Chemical & Pharmaceutical Bulletin”

This study found that several synthesized pregnane derivatives exhibited significant inhibitory effects on testosterone conversion to dihydrotestosterone and reduced related androgenic parameters in multiple pharmacological models.

research New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors

14 citations , June 2011 in “Steroids”

This study found that several dehydroepiandrosterone ester derivatives effectively reduced prostate and seminal vesicle weight in gonadectomized hamsters treated with testosterone, demonstrating potential antiandrogen effects comparable to Finasteride.

research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors

13 citations , January 2005 in “Chemical and Pharmaceutical Bulletin”

This study reported that newly synthesized progesterone derivatives significantly reduced prostate weight in testosterone-treated hamsters, with 5alpha-reductase inhibitory activity dependent on the size of the substituent at C-17.

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community Does whey protein and creatine aggravate hair loss?

79 upvotes 2 years ago

The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

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