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In this study, the authors used AI-driven methods to identify and prioritize promising therapeutic targets that may address both aging and Glioblastoma Multiforme, proposing CNGA3, GLUD1, and SIRT1 as novel candidates.

In this study, elevated mRNA levels for serine-rich ultra high sulfur proteins were observed during active hair growth phases in mice, particularly in the forming hair structures and upper skin layers.

This study found that Gp₄G increased hair length, papilla cell numbers, and versican deposition in treated animals, potentially through alterations in hair follicle phases and nucleotide concentrations.

This study investigated the production of β-cyclodextrin from ginkgo seeds, finding that a pretreatment scheme involving high-temperature gelatinization significantly improved the conversion rate to 72.63%, highlighting the industrial potential of underutilized ginkgo seed powder for sustainable applications.

This paper presents a new device for navigational surgery utilizing the fluorescent properties of Indocyanine Green, offering enhanced intra-operative imaging capabilities by identifying tissues with an infrared CMOS camera.

This article reviews the role of glycogen synthase kinase-3 in various diseases and recent developments in GSK-3 inhibitors, without reporting any new clinical findings.

This study found that GLI2 plays a key role in activating follistatin, an activin/BMP antagonist, in response to hedgehog signaling in human epidermal cells, with implications for hair follicle development and basal cell carcinoma.

This study observed that GPT-4o, a generative AI model, showed high concordance with human providers in automating image-based SALT scores for assessing alopecia areata, suggesting its potential in assisting clinical evaluations without additional training.

In this study, small molecule-loaded silk fibroin nanofiber scaffolds with chitosan achieved sustained release of GSK-3 inhibitor SB216763, leading to enhanced wound healing and hair follicle neogenesis in skin regeneration efforts.

This study found that a gintonin-enriched fraction from ginseng promoted hair growth in mice by stimulating dermal papilla cell proliferation and increasing hair follicles and weight.

This study found that the GPR39 receptor plays a novel role in accelerating wound healing in mouse skin, although it is not essential for skin development or homeostasis.

This study demonstrates that a single exposure to GHB during a sexual assault can be detected by analyzing hair segments collected about one month after the incident.

This study found that notch1 signaling is severely impaired in hidradenitis suppurativa patients with or without NCSTN or other gamma-secretase gene mutations, highlighting a canonical defect at the lesional tissue level.

This study found that GS-KG9 and GS-E3D, bioactive ginseng extracts, reduced BBB disruption and neuronal apoptosis in the hippocampus of diabetic rats, suggesting potential therapeutic effects for diabetic patients.

This study found that sacituzumab govitecan improved health-related quality of life in most areas for patients with HR+/HER2− metastatic breast cancer compared to chemotherapy, except for increased diarrhea, supporting its use as a treatment option.

This study found that SDG did not significantly affect prostate weight in rats with BPH, but it may reduce serum PAP activity and alter prostate tissue changes induced by Testosterone Propionate.

This study found that modified laparoscopic sleeve gastrectomy in patients with type 2 diabetes and obesity reduced ghrelin levels, improved glycemic and insulin levels, and resulted in significant weight loss.

This study found that the S100A4/NMIIA axis contributes to glioblastoma progression by recruiting and promoting migration of GBM cells along blood vessels, correlating with worse patient outcomes.

In this study, researchers established that increased expression of the human GLI-1 gene in mouse skin leads to the development of tumors that closely resemble human basal cell carcinomas, without requiring additional mutations in the p53 or Ha ras genes.

This study found that WISP-1 plays a key role in ligamentum flavum fibrosis through the Hedgehog-Gli1 pathway, with cyclopamine showing potential to reduce fibrosis effects in a rabbit model.

This study found no association between serum concentrations of irisin or GIP and BMI in women with or without PCOS.

In this study, a TGF-β mimic molecule from Heligmosomoides polygyrus was observed to enhance wound healing in mice, with improved tissue regeneration and specific immune cell recruitment without increased scarring.

This study found that robotic training with the Ekso-GT significantly improved body representation and quality of life in spinal cord injury patients compared to conventional physical therapy.

This study analyzed the Chinese version of the Symptom Checklist-90 and suggested revising 18 items to improve its quality and relevance.

This study found that GD-23, a dipeptide ligand of TSPO, exhibited an anxiolytic effect in the elevated plus maze test, which was inhibited by selective neurosteroid synthesis inhibitors, suggesting a neurosteroidogenic mechanism.

This case report describes a 12-year-old boy with severe skin scaling due to novel compound heterozygous null truncation mutations in the TGM1 gene, resulting in loss of transglutaminase 1 activity.

This study found that age, pre-pregnancy BMI, and family history of diabetes were independent predictors of gestational diabetes in Iranian women, with selective screening missing few cases among low-risk groups.

This article introduces signatureSearch, a software package designed for gene expression signature searching and functional enrichment analysis, but reports no new clinical results.

This study identified genomic regions and candidate genes that may contribute to phenotypic diversity in coat color, body size, cashmere traits, and high-altitude adaptation in domesticated goat breeds.

This bibliometric analysis identified SGK1 as a key factor in cancer, showing that its dysregulation can lead to tumor growth and treatment resistance. The authors highlighted SGK1's potential as a therapeutic target, but note that further research is needed to develop effective treatment strategies.