March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, the researchers described a formulation process for Ratanjot hair oil using Alkanna tinctoria roots, reporting traditional uses of the oil in preventing hair loss, baldness, premature greying, and promoting hair growth, but did not present empirical results.
7 citations
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March 1990 in “Pigment Cell Research” This animal study observed that while topical MBEH and intraperitoneal phenol induced hair graying in eumelanic mice, they had little effect on pheomelanic mice, and amcinonide reduced certain epidermal melanocytes in both.
December 2025 in “Skin Appendage Disorders” This case report, one of the youngest on record, suggests that systemic stress might trigger pediatric sudden hair graying linked with diffuse alopecia areata, emphasizing the need to differentiate it from congenital silvery hair syndromes due to their distinct prognosis and treatment options.
This review reports the first known case of hair repigmentation associated with lamivudine use and examines mechanisms related to drug-induced hair repigmentation, suggesting potential therapeutic strategies for reversing hair graying.
1 citations
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June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that modulating epithelial and mesenchymal cell interactions in vitro enabled nearly 100% efficient induction of hair follicles, suggesting potential applications for understanding and testing hair growth and graying.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the potential of ridge gourd (Luffa acutangula) in promoting healthy hair growth due to its nutrients and antioxidants, with suggestions of benefits such as follicle strengthening and delaying graying, though it calls for more clinical studies to verify these effects.
November 2023 in “The Bovine practitioner” In this study, a 5-year-old Angus bull experienced systemic granulomatous disease and vasculitis potentially associated with grazing on hairy vetch, but other bulls in the same pasture showed no symptoms, suggesting variability in disease manifestation from similar exposures.
June 2024 in “British Journal of Dermatology” In this case report, an 80-year-old woman experienced darkening of previously grey hair, which may be linked to vitamin B supplementation, though its effectiveness is typically associated with reversing greying only in the presence of an initial vitamin B deficiency.
3 citations
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January 2018 in “Open Access Macedonian Journal of Medical Sciences” In this study, the use of Biofibre hair implants showed significant improvements in scalp coverage and Hamilton scale grading for 97.94% of male and female patients with androgenetic alopecia after two years, with minimal and manageable side effects reported.
7 citations
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January 2023 in “Animals” This study found that supplementing pregnant cashmere goats' diets according to nutritional standards improved their fiber production, growth, fertility, and the development of kids' secondary hair follicles.
July 2022 in “Journal of Investigative Dermatology” The combination of a plant extract and a peptide can increase hair pigmentation and may reverse greying.
5 citations
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January 1976 Under the conditions of this research, Leucaena was generally unpalatable for heifers, caused health issues like goitre and hair loss, and did not significantly increase fertility or productivity.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study examined the formulation of an oil derived from Alkanna tinctoria roots, traditionally used for hair health, and discusses its potential benefits for controlling hair loss, baldness, and premature greying, while promoting hair growth.
January 2022 in “Indian journal of paediatric dermatology” In this study, patients with premature graying of hair had lower levels of zinc, magnesium, and Vitamin B12 compared to healthy controls.
2 citations
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January 2023 in “International journal of biological sciences” This review discusses the mechanisms of hair repigmentation and reports no clinical results; the authors suggest further research into topical treatments for reversing gray hair.
5 citations
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June 2019 in “Dermatopathology” This study found poor agreement among dermatopathologists in identifying and grading fibrosis in traction alopecia, suggesting the need for better diagnostic methods for early fibrosis detection.
This article discusses the potency grading of steroid skin creams and highlights that very potent or potent steroids (grades I and II) can cause significant side effects, especially in children.
1 citations
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April 2018 in “International journal of Ayurvedic medicine” This review discusses Ayurvedic approaches to premature greying of hair, focusing on detoxifying therapies like panchakarma and various rejuvenative treatments, but presents no new empirical findings.
July 2025 in “International Journal of Medicine Sciences” This case study observed that an integrated treatment combining homeopathy and bioengineered hair therapy led to significant improvements in hair density, reduced hair fall, and emotional well-being for a woman with androgenetic alopecia.
July 2018 in “Elsevier eBooks” This chapter reviews traction alopecia, discusses its clinical presentation and severity grading, and reports no new clinical results; the authors highlight controversies in its treatment and prevention strategies.
July 2025 in “Pigment International” This case report highlights a 40-year-old Indian male diagnosed with follicular vitiligo, presenting as graying hair and depigmented patches, and emphasizes the importance of distinguishing this rare variant from similar conditions like alopecia areata due to its unique presentation.
23 citations
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November 2007 in “Actas Dermo-Sifiliográficas” This study suggests that topical T3 can induce hair follicles to enter the growth phase and may reverse graying in mice, with in vitro results supporting enhanced hair shaft growth.
2 citations
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November 2024 in “JAAD reviews.” This review reported that certain systemic drugs, including antiepileptics and anticancer drugs, can lead to changes in hair pigmentation, such as hypopigmentation or hyperpigmentation, with varied prevalence and clinical characteristics.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the formulation and evaluation of herbal hair serums, highlighting the use of natural ingredients like fenugreek, hibiscus, and kalonji, which are claimed to improve hair strength and scalp health.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review details the formulation, ingredients, and evaluation of herbal hair serum, noting its potential to improve hair texture and scalp health through the use of natural phytoconstituents.
April 2022 in “Journal of advances in medicine and medical research” This study found that applying topical minoxidil 5% twice daily for 24 weeks increased hair density and width in men with androgenetic alopecia, although the change in clinical hair grading was not statistically significant.
This review highlights Neelibhringadi Hair Oil as a traditional Ayurvedic option for managing hair issues like dandruff and thinning, supported by its antioxidant and anti-inflammatory properties, but emphasizes the need for modern clinical trials to confirm its effectiveness.
99 citations
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June 2005 in “Journal of Cosmetic Dermatology” This article reviews factors influencing hair aging and available treatments like minoxidil and finasteride for androgenetic alopecia but reports no new clinical results.
1 citations
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September 2013 in “Elsevier eBooks” This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.
August 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.