SnapshotDx Quiz: May 2022

April 2022 in “ Journal of Investigative Dermatology ”

Jordan Phillipps, Neel S. Raval, Amy Musiek

androgenetic alopecia AGA androgens hair thinning follicular miniaturization bitemporal thinning vertex thinning androgen receptor activity topical minoxidil finasteride telogen effluvium central centrifugal cicatricial alopecia trichotillomania alopecia areata sisaipho androgenic alopecia Rogaine Propecia

TLDR Androgenetic alopecia causes hair thinning due to increased androgen activity, treatable with minoxidil and finasteride.

The "SnapshotDx Quiz: May 2022" from the Journal of Investigative Dermatology focuses on diagnosing androgenetic alopecia (AGA), a common form of hair loss affecting up to 50% of males and females. AGA is characterized by a heightened response to androgens, leading to progressive hair thinning and follicular miniaturization. The quiz highlights that AGA typically presents with bitemporal thinning in men and vertex thinning in women. The pathogenesis involves increased androgen receptor activity, and first-line treatments include topical minoxidil and finasteride. The document also discusses differential diagnoses such as telogen effluvium, central centrifugal cicatricial alopecia, trichotillomania, and alopecia areata sisaipho, providing detailed descriptions and distinguishing features for each condition.

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