701 citations,
August 2014 in “Nature medicine” Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.
21 citations,
December 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
9 citations,
September 1997 in “Dermatologic Surgery” The technique of transplanting micrografts in hair restoration surgery is fast, practical, and efficient, minimizing damage to follicles and grafts.
27 citations,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
February 2023 in “Facial Plastic Surgery Clinics of North America” Careful planning and skilled surgery can make hair replacement safe and effective.
12 citations,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
31 citations,
August 2019 in “Regenerative Medicine” Human placenta hydrogel helps restore cells needed for hair growth.
30 citations,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
236 citations,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
184 citations,
November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
42 citations,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
33 citations,
September 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Human hair follicle dermal cells can effectively replace other cells in engineered skin.
27 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Somatostatin may help protect hair follicles from immune attacks.
13 citations,
May 2005 in “Seminars in Plastic Surgery” Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.
9 citations,
April 2000 in “Plastic and Reconstructive Surgery” The document concludes that appearance can be significantly improved after one hair restoration correction procedure, but often multiple operations are needed for the best results.
Follicular unit grafting is a procedure used to treat hair loss, where small hair grafts are placed into the scalp, with future treatments likely to involve smaller incisions and cell-based therapies.
January 2017 in “Springer eBooks” Scientists made working hair follicles using stem cells, helping future hair loss treatments.
113 citations,
September 2005 in “Journal of Investigative Dermatology” Applying a special compound can promote hair growth without harmful side effects.
50 citations,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
46 citations,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
30 citations,
December 2017 in “Advanced Healthcare Materials” Nanoencapsulation creates adjustable cell clusters for hair growth.
18 citations,
October 2014 in “Experimental Biology and Medicine” Eating vitamin A affects hair growth and health by changing cell signals in mice.
17 citations,
February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
15 citations,
May 2004 in “Facial Plastic Surgery Clinics of North America” New techniques in hair restoration surgery can fix unnatural results from old methods, improving patient self-esteem.
14 citations,
February 2014 in “Experimental Cell Research” The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
13 citations,
January 2022 in “Stem cell reviews and reports” Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
10 citations,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
April 2019 in “Journal of Investigative Dermatology” Differences in growth factors in platelet-rich plasma therapy for hair loss can vary between patients and can be influenced by the devices used, possibly leading to inconsistent results.