Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This report suggests that in vitiligo, melanocytes may be destroyed by the same factors necessary for melanin production, contributing to the skin's depigmentation.

This study found that oxidative stress in hair follicle melanocytes contributes to premature aging and apoptosis, providing insights into graying as a model for studying aging and testing antiaging therapies.

This study found that oral isotretinoin achieved good to excellent clinical results in treating severe inflammatory acne, severe rosacea, and gram-negative folliculitis.

This study reported that transgenic mice with targeted TNF alpha expression in keratinocytes showed impaired weight gain, retarded hair growth, and skin changes, leading to cachexia and necrosis.

In this study, co-grafting human keratinocytes with murine dermal papilla-enriched cells produced hair follicle-like structures, but without regular hair formation, suggesting anomalous folliculogenesis.

This study found that three wall orbital decompression by the coronal approach effectively reduces proptosis in Graves' ophthalmopathy patients with fewer complications compared to other techniques.

This study observed that human hair follicles were able to regenerate fiber-forming structures after the bulb was amputated and transplanted onto athymic mice, suggesting a general regenerative capacity.

This study observed that 19% of patients with Graves' orbitopathy experienced induced diplopia after orbital decompression, with high patient satisfaction reported following both coronal and translid approaches.

This study found that proanthocyanidins from grape seeds significantly promote hair follicle cell proliferation and hair cycle transition in mice, suggesting their potential as hair growth agents.

This article describes the skin changes seen in acute and chronic graft-vs-host reactions after bone marrow transplantation, highlighting the potential for early recognition due to the visibility of these changes, but reports no new clinical results.

This case report describes an HIV-infected patient on HAART who developed autoimmune diseases, including alopecia universalis and Graves' disease, associated with immune restoration after CD4 cell count increases.

In this study, phenylthiocarbamide intake was associated with hair graying in rats, while switching to tap water led some rats to regain their original fur color, suggesting dietary factors influence pigmentation.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.

This review describes techniques for successful skin grafting and variations of the procedure, reporting no new clinical results.

This study demonstrated that cultured human dermal papilla cells can induce full hair follicle formation when combined with neonatal foreskin keratinocytes in a grafted dermal-epidermal construct on mice.

This report describes a case of granulomatous reaction to injectable poly-L-lactic acid in the periorbital area and suggests surgical excision as an effective treatment for persistent nodules.

This study found that trichohyalin, a protein previously thought to be restricted to hair and tongue, is also present in isolated cells within the granular layer and stratum corneum of normal human epidermis.

This review examines the pathogenesis of premature hair graying and potential treatment avenues, but reports no new experimental outcomes, highlighting ongoing research challenges and hopes for drug development.

This study found that compromised antioxidant activity in gray hair follicles affects both mature melanocytes and their immature precursors, linked to down-regulation of melanogenesis-related genes.

This review explores the role of Granzyme B in autoimmune skin diseases and highlights its potential as a therapeutic target due to its involvement in impaired barrier function and inflammation.

This study found that serum calcium, serum ferritin, and vitamin D3 levels were lower in students with premature graying of hair compared to controls, suggesting a potential role in the condition.

This study found that cotreatment with graphene oxide and indole-3-acetic acid significantly inhibited root development in Brassica napus, with the inhibition increasing as indole-3-acetic acid concentration rose.

This study suggests that higher PDCD4 expression may play a significant role in polycystic ovary syndrome pathogenesis through its association with obesity, insulin resistance, lipid metabolism disorders, and increased granulosa cell apoptosis.

This study found that inadequate maternal pyridoxine during pregnancy led to lower body weight, slow physical development, and impaired neuromotor development in rat pups, with the severity increasing as pyridoxine levels decreased.

This study found that topical ruxolitinib protected Lgr5+ skin stem cells and maintained skin homeostasis in skin GVHD, unlike corticosteroids.

This article describes incisional slit grafting as an improved hair transplantation method, using smaller grafts and conserving vascular supply to enhance graft yield and achieve a more natural hairline, but reports no new research results.

In this case report, a patient with Hodgkin's disease treated with ABVD chemotherapy became disease-free, and accompanying granuloma annulare skin lesions also improved.

This study found that ionizing radiation primarily affects keratinocyte stem cells in the hair follicle, suggesting they play a central role in radiation-induced hair graying, rather than melanocyte stem cells.

This review discusses medication-induced gray hair repigmentation, highlighting that certain anti-inflammatory drugs and melanogenesis stimulators can cause diffuse repigmentation, though evidence remains low-quality and these medications are not currently indicated for this purpose.