May 2026 in “Aesthetic Plastic Surgery” This study found that autologous growth factor injections for androgenetic alopecia improved hair density, thickness, and patient satisfaction over 12 months; however, high bias risk and non-standardized methods limit the evidence's reliability, highlighting the need for larger, standardized trials.
March 2026 in “Preprints.org” This review suggests that the compound DRDE-07, originally a sulphur-mustard countermeasure candidate, could potentially be repurposed for skin protection due to its compatibility with pathways involved in oxidative stress and inflammation, though further experimental study is needed to confirm its therapeutic applicability in dermatology.
This review presents evidence supporting acupuncture's potential benefits for AA treatment but notes the findings are limited by low-quality evidence and small sample sizes, suggesting a need for future large-scale, rigorous studies.
November 2025 in “Basic and Clinical Andrology” This systematic review and meta-analysis found that male first-degree relatives of women with PCOS have increased rates of metabolic issues, hormonal imbalances, and androgenic features compared to controls, suggesting a male equivalent of PCOS.
October 2025 in “International Journal of Molecular Sciences” This study identified changes in immune activation, ferroptosis, and structural genes in alopecia areata subtypes, suggesting molecular markers that might help understand disease variability and guide future treatments.
October 2025 in “International Journal of Women’s Dermatology” In a cross-sectional analysis of 58 hair growth cosmeceuticals marketed for women or unisex use, this study found that ingredients with potential environmental hazards, particularly phenoxyethanol and synthetic fragrances, are commonly present, while substances like sodium lauryl sulfate, parabens, and microbeads were not detected.
August 2025 in “Lasers in Medical Science” In this study, the combination of low-level laser therapy and topical minoxidil was found to improve hair density and diameter more effectively than minoxidil alone in treating androgenic alopecia, with similar safety profiles observed in both groups.
August 2025 in “International Journal of Molecular Sciences” This meta-analysis found that among topical OTC treatments for male androgenetic alopecia, minoxidil 5% applied twice daily was the most effective in increasing total hair density over 24 weeks.
August 2025 in “Archives of Dermatological Research” This systematic review and meta-analysis suggest that oral minoxidil may be a safer and more effective option for children with hair disorders and refractory hypertension, though further large-scale trials are needed.
April 2025 in “Frontiers in Medicine” This bibliometric analysis reviewed 4,515 articles on strabismus research from 2004 to 2023, highlighting a shift towards innovative and interdisciplinary treatment methods, with significant contributions noted from the USA, China, and the UK.
April 2025 in “Journal of Diabetes & Metabolic Disorders” This study found that linc-PINT expression was significantly decreased in patients with atrial fibrillation compared to healthy controls, while several TGF-β signaling genes were increased, suggesting a potential role in heart arrhythmias' pathogenesis.
February 2025 in “International Journal of Molecular Sciences” This meta-analysis of animal studies found that alkaloids have potential anti-influenza and anti-inflammatory effects, correlating with improved viral titers and survival rates, though they did not effectively reduce TNF-α and IL-6 levels. Extensive further studies are needed to confirm these findings before considering clinical application.
January 2025 in “BMC Genomics” In this study, researchers identified thousands of mRNA, lncRNA, circRNA, and miRNA transcripts involved in different hair follicle stages of Rex rabbits and highlighted significant gene expression changes and pathway enrichments, providing insights into the regulatory mechanisms of hair development in these animals.
This study observed that TBX3 mRNA expression levels were region-specific and correlated with pigmentation patterns in dun Mongolian horses, providing insights into the genetic mechanisms behind their distinctive Bider markings.
November 2024 in “Archives of Dermatological Research”
March 2024 in “Journal of Endocrinological Investigation” This study on male rats found that finasteride treatment led to the differential expression of several genes in the hypothalamus and hippocampus, hinting at potential links to observed side effects like depression, anxiety, and cognitive disturbances.
December 2023 in “Lasers in Medical Science” Fractionated laser therapy, especially erbium-glass laser, effectively increases hair thickness in people with hair loss but doesn't increase the number of hairs.
November 2023 in “Children” In this study, valproic acid, levetiracetam, and phenytoin were the main anti-seizure medications associated with adverse drug reactions in pediatric epilepsy patients, with younger children and those on polytherapy at higher risk.
September 2023 in “Nature Communications” In this study, the researchers found that rare genetic variants make a minor contribution to male-pattern hair loss risk, identifying five significant gene associations, including novel genes, and noting a shared basis with monogenic hair loss disorders.
September 2023 in “Archives of Dermatological Research” Using minoxidil with microneedling increases hair count for hair loss without serious side effects.
September 2023 in “Middle East Fertility Society Journal” This study found that nicotine may have a therapeutic role in mitigating the exacerbation of infertility conditions connected with alpha-synuclein-related Parkinson’s disease through molecular interactions identified via pathway analysis.
August 2023 in “Aesthetic Plastic Surgery” This meta-analysis found that PRP monotherapy improved hair density in androgenetic alopecia patients but did not affect hair diameter, with stronger effects observed in male subjects.
August 2023 in “Frontiers in Endocrinology” This study identified novel mitochondrial DNA variations in PCOS patients from Pakistan, which may serve as genetic predisposition markers, highlighting especially the potential pathogenicity of frameshift mutations in the MT-ND2 gene.
October 2022 in “Frontiers in Genetics” This study found that miRNAs increase and target mRNAs and lncRNAs decrease from the anagen to telogen phase in mouse hair follicles, and these ceRNA networks may play a role in hair follicle cycling.
May 2022 in “Clinical Epigenetics” This study found that maternal early-pregnancy serum ferritin concentrations were associated with lower DNA methylation levels at specific CpG sites in cord blood, with some associations persisting into childhood.
January 2017 in “The Journal of Korean Medicine Ophthalmology&Otorhinolaryngology&Dermatology” This study found that early-onset male androgenetic alopecia is significantly associated with an increased risk of metabolic syndrome.
May 2001 in “Hair transplant forum international” This article discusses the use of a high-magnification digital video microscope for diagnosing and treating androgenetic alopecia and reports no new clinical results.
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July 2022 in “Biomedicines” This study found no significant difference in the severity of alopecia areata between treatments with platelet-rich plasma and triamcinolone acetonide; further high-quality trials of PRP are needed.
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August 2025 in “International Journal of Molecular Sciences” This study found that women with PCOS have significantly higher prevalence and levels of thyroid autoantibodies, with these elevated levels suggesting a potential independent autoimmune activation associated with PCOS.
This study found that a data-driven model using XGBoost effectively predicts individualized responses to minoxidil for androgenetic alopecia, outperforming traditional methods in accuracy and reliability.