Prevalence and Levels of Thyroid Autoantibodies in Polycystic Ovary Syndrome—Impact of TSH- and BMI-Matched Comparisons: A Systematic Review and Meta-Analysis

    August 2025 in “ International Journal of Molecular Sciences ”
    Jakub Kwiatkowski, Nicole Akpang, Łucja Zaborowska, Artur Ludwin
    Studysummary This study found that women with PCOS have significantly higher prevalence and levels of thyroid autoantibodies, with these elevated levels suggesting a potential independent autoimmune activation associated with PCOS.
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    Research cited in this study 7

    1. Physiopathology of Polycystic Ovary Syndrome in Endocrinology, Metabolism, and Inflammation Journal of Ovarian Research · 2025
    2. Beyond Hormones: A Systematic Review of the Risk of Cardiovascular Diseases in Polycystic Ovary Syndrome Cureus · 2024
    3. Pharmacological Management of Polycystic Ovary Syndrome Australian Prescriber · 2024
    4. Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome The Journal of Clinical Endocrinology and Metabolism · 2023
    5. Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing International Journal of Molecular Sciences · 2022
    6. Obesity and Polycystic Ovary Syndrome: Implications for Pathogenesis and Novel Management Strategies Clinical medicine insights · 2019
    7. High Prevalence of Chronic Thyroiditis in Patients with Polycystic Ovary Syndrome European Journal of Obstetrics & Gynecology and Reproductive Biology · 2013