research Improving Selective Androgen Receptor Modulator Discovery and Preclinical Evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
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research Hyperandrogenism from an Ovarian Interstitial-Cell Tumor in an Alpaca
An alpaca acted like a male and couldn't have babies because of a benign tumor in its ovary that caused high testosterone levels.
research Androgens and Hair: A Biological Paradox
Androgens can cause hair growth in some areas but hair loss on the scalp.
research Other Antiandrogens: Alternative Treatments for Acne and Hirsutism
Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
research Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia
Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
research Effect of Immunization Against Melatonin on Seasonal Fleece Growth in Feral Goats
Immunizing goats against melatonin can temporarily change their cashmere growth cycles and increase fleece production.
research Controversies in Plastic Surgery: Suction-Assisted Lipectomy and the hCG Protocol for Obesity Treatment
The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.
research Biotinidase Deficiency Characterized by Skin and Hair Findings
Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.
research Androgenetic Alopecia: Effects of Oral Finasteride on Hormone Profile, Reproduction, and Sexual Function
Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.
research The Eye and the Skin in Endocrine Metabolic Diseases
Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.
research Management of Recurrent Ischemic Priapism: A Complex Condition with Devastating Consequences
Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.
research Polycystic Ovary Syndrome: Features, Diagnostic Criteria, and Treatments
PCOS is a long-term condition that needs more research for better understanding and treatment.
research Androgens and Acne: Perspectives on Clascoterone, the First Topical Androgen Receptor Antagonist
Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
research CYP21A2 Mutations in Women with Polycystic Ovary Syndrome
Mutations in the CYP21A2 gene are not a major factor in causing PCOS.
research The Androgen Receptor Gene Polyglycine Repeat Polymorphism Is Associated With Memory Performance In Healthy Chinese Individuals
Certain gene variations are linked to better memory in healthy Chinese women.
research Combination of an Antiandrogen and a 5α-Reductase Inhibitor: A Further Step Towards Total Androgen Blockade?
Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
research Disappearing Foot Disease: An Unusual Presentation of Primary Lymphoma of Bone
An elderly woman's swollen, painful foot was found to be caused by a rare type of bone lymphoma, which improved with radiation treatment.
research A Falling Out Following Minoxidil: Telogen Effluvium
A man lost a lot of scalp hair quickly after stopping minoxidil, but it grew back with mild male pattern baldness.
research Hair Loss
Hair loss has many causes and treatments, and losing some hair daily is normal; proper diagnosis is key, and minoxidil can help treat it.
research Age-Specific Cut-Off Levels of Anti-Müllerian Hormone as Diagnostic Markers for Polycystic Ovary Syndrome
Different levels of anti-Müllerian hormone can help diagnose polycystic ovary syndrome in women of different ages.
research Role of 5α-Dihydrotestosterone in Testicular Development of Gilthead Seabream Following Finasteride Administration
DHT affects testicular development and regulates spermatogenesis in some fish.
research Transcriptomic Profiling in Silurana Tropicalis Testes Exposed to Finasteride
Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
research Androgens and Hair: A Biological Paradox with Clinical Consequences
Androgens can both increase body hair and cause scalp hair loss.
research Variations in Alanine Aminotransferase Levels Within the Normal Range Predict Metabolic and Androgenic Phenotypes in Women of Reproductive Age
Normal-range ALT levels can indicate metabolic and hormonal imbalances in young women.
research Preponderance of Serum and Intra-Hepatic 5α-Dihydrotestosterone in Males with Hepatocellular Carcinoma Despite Low Circulating Androgen Levels
Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.
research Evaluation of Quality of Life of Patients with Hirsutism Among Turkish Women: A Single-Center Cross-Sectional Study
Turkish women with hirsutism experience lower quality of life, especially those with PCOS, regardless of hair growth severity.
research 11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research Circulating and Intraprostatic Sex Steroid Hormonal Profiles in Relation to Male Pattern Baldness and Chest Hair Density Among Men Diagnosed with Localized Prostate Cancers
Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
research Can Serum Vaspin Levels Predict Clomiphene Resistance in Infertile Women with PCOS?
Lower vaspin levels in the blood may indicate a better response to fertility treatment in women with PCOS.
research The Effect of Simvastatin on Plasma Steroid Hormone Levels in Metformin-Treated Women with Non-Classic Congenital Adrenal Hyperplasia
Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.