TLDR Different levels of anti-Müllerian hormone can help diagnose polycystic ovary syndrome in women of different ages.
The study conducted by Ramezani Tehrani et al. included 803 women aged 20-40, with 303 diagnosed with PCOS and 500 as controls, and aimed to establish age-specific AMH cut-off levels for diagnosing PCOS. The research found optimal AMH cut-offs at ages 27 and 35, with levels of 5.7 ng/ml for ages 20-27, 4.55 ng/ml for ages 27-35, and 3.72 ng/ml for ages 35-40. High PPVs and NPVs were observed for these cut-offs, indicating their effectiveness in discriminating PCOS across different age categories. The study concludes that age-specific AMH levels can accurately assess the presence of PCOS in women of reproductive age, with the Bayesian method providing a reliable approach for determining these cut-offs.
30 citations,
November 2018 in “Fertility and Sterility” Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.
221 citations,
January 2014 in “Human Reproduction” Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.
28 citations,
April 2013 in “Fertility and Sterility” Caucasian and Asian women with PCOS generally show similar symptoms, except Asian women have less chest hair.
51 citations,
November 2011 in “Reproductive Biology and Endocrinology” About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.
215 citations,
January 2011 in “Reproductive Biology and Endocrinology” About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.
1540 citations,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
4025 citations,
December 2003 in “Human Reproduction” The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
16 citations,
September 2018 in “Clinical Biochemistry” The document concludes that more research is needed to fully understand the causes of PCOS.
August 2023 in “İzmir tepecik eğitim hastanesi dergisi” Vitamin D levels do not significantly relate to the causes of PCOS or DOR in infertile patients.
30 citations,
April 2014 in “Seminars in Reproductive Medicine” Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.
43 citations,
October 2019 in “Pediatric Research” Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
January 2025 in “The Journal of Clinical Endocrinology & Metabolism” Diagnosing PCOS is challenging due to its complex and varied symptoms.
