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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

LncRNA MTC boosts growth of goat skin cells, improving cashmere quality.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

Polish medical societies recommend personalized treatment for PCOS based on the patient's specific symptoms and use the Rotterdam criteria for diagnosis.

PRX102 is essential for rice root hair growth by helping transport substances to the tips.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

Some chemicals absorbed through the skin can cause serious health problems.

Caffeic acid helps protect rats from the harmful effects of acrylamide.

Jujube fruit extract may reduce kidney damage from ibuprofen in rats.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

People with a common type of hair loss have higher stress levels in their body, and treatments that reduce this stress could help.

Essential oils may improve dogs' health and melatonin can help with their sleep and anxiety, but both should be used carefully.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Activating Nrf2 can help protect against hearing loss.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Ischemic modified albumin could be a new indicator of oxidative stress in people with alopecia areata.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.