LncRNA MTC Enhances the Proliferation of Liaoning Cashmere Goat Skin Fibroblasts by Modulating GSTM1-ASK1 Interaction

    March 2024 in “ Cytologia ”
    Mei Jin, Miaogen Chen, Weiyu Fan … Xinyue Qiu
    Studysummary In this study, researchers observed that melatonin-mediated LncRNA MTC in Liaoning cashmere goat skin fibroblasts enhances cell proliferation by interacting with the GSTM1 protein, affecting its complex formation with ASK1 and thereby inhibiting apoptosis, which may be relevant for improving cashmere growth.
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    Research cited in this study 6

    1. Melatonin Promotes Secondary Hair Follicle Development in Early Postnatal Cashmere Goats and Improves Cashmere Quantity and Quality by Enhancing Antioxidant Capacity and Suppressing Apoptosis Journal of Pineal Research · 2019
    2. Long Noncoding RNA and Gene Expression Analysis of Melatonin-Exposed Liaoning Cashmere Goat Fibroblasts Indicating Cashmere Growth Naturwissenschaften · 2018
    3. Transcriptome Reveals Long Non-Coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin Frontiers in physiology · 2018
    4. Integrated Analysis of Coding Genes and Non-Coding RNAs During Hair Follicle Cycle of Cashmere Goat (Capra Hircus) BMC Genomics · 2017
    5. Does Maternal Exposure to Artificial Food Coloring Additives Increase Oxidative Stress in the Skin of Rats? Human & Experimental Toxicology · 2016
    6. The Role of Neprilysin in Regulating the Hair Cycle PLoS ONE · 2013