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CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Diuretics can cause serious side effects and should be used carefully.

Early diagnosis and treatment of TPP can prevent complications.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.

Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.

Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.

New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

The visfatin GT genotype may increase the risk of Alopecia Areata.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Activating Nrf2 can help protect against hearing loss.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Special cell particles from macrophages can help hair grow.

Certain gene variations may protect against skin issues and oxidative stress in women with PCOS.

Researchers found genes linked to hair growth cycles in Inner Mongolia cashmere goats, which could help understand and treat hair loss.

Creatine monohydrate is safe and effective for muscle recovery and performance, especially for those with low creatine levels.

N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.

People with plantar corns and calluses may have a higher chance of having metabolic syndrome.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Women with PCOS who have high male hormone levels often also have insulin resistance.