Investigation of Vaspin and Visfatin -4689G/T Gene Polymorphisms in Alopecia Areata Patients

August 2024 in “ OSMANGAZİ JOURNAL OF MEDICINE ”

Fulya Yükçü, Raziye Akçılar, Nazlı Dizen Namdar, Sevgi Koçyiğit Sevinç

vaspin visfatin gene polymorphisms Alopecia Areata AA genotypes allele distribution GT genotype GG genotype

Studysummary This study reported no significant association between vaspin and visfatin -4689G/T gene polymorphisms and alopecia areata in the Turkish population, although the visfatin GT genotype may pose a risk factor for the condition.

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This study investigated the relationship between vaspin and visfatin -4689G/T gene polymorphisms and Alopecia Areata (AA) susceptibility in 80 AA patients and 80 healthy controls from the Turkish population. The results showed no significant difference in vaspin genotypes and allele distribution between AA patients and controls. However, the visfatin GT genotype was more prevalent in AA patients, indicating a higher likelihood of AA compared to the GG genotype [OR (95% CI) = 2.11 (1.04-4.27), p = 0.03]. The study concludes that while vaspin polymorphisms are not associated with AA, the visfatin GT genotype may be a risk factor for AA.

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Investigation of Vaspin and Visfatin -4689G/T Gene Polymorphisms in Alopecia Areata Patients

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