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Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

CDP is crucial for lung and hair follicle cell development.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Clobetasol propionate ointment can help some people with total hair loss regrow hair.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Flutamide rarely causes liver toxicity in prostate cancer patients.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.