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Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Three-dimensional culture helps dermal papilla cells grow new human hair follicles.

The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.

3D scaffolds mimicking the extracellular matrix are crucial for effective hair follicle regeneration.

YAP1 is important for skin regeneration and may affect skin disorder treatments.

The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.

The book explains the science of tissue repair and regeneration, its medical uses, challenges, and ethical concerns.

Creating fully functional artificial skin for chronic wounds is still very challenging.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

The document concludes that more research is needed on making and understanding biomaterial scaffolds for wound healing.

Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.

Telocytes might help with skin repair and regeneration.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The technique can potentially treat hair loss by using a matrix to grow new hair from cells.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

After skin is damaged, noncoding dsRNA helps prostaglandins and Wnts work together to repair tissue and promote hair growth.

The anti-CXCL4 antibody helps mice grow hair faster and prevents hair loss.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

The hydrogel helps heal wounds and regrow hair by mimicking a baby's environment.

Skin organoids from stem cells could better mimic real skin but face challenges.

The hydrogel with silver and mangiferin helps heal wounds by killing bacteria and aiding skin and tissue repair.

Ellagic acid may help regrow hair and prevent hair loss by activating a specific cell growth pathway.

Keratin 79 is linked to liver damage and may help diagnose liver diseases.

Combining SVF and PRP speeds up wound healing.

Stem cell therapies show promise for hair regrowth in androgenetic alopecia.