44 citations
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March 2015 in “PLOS ONE” This study found that FGF-9 treatment in diabetic mice improved heart function after myocardial infarction by decreasing monocyte infiltration and promoting anti-inflammatory macrophage differentiation.
May 2022 in “Journal of Cosmetic Dermatology” This study found that concentrated growth factor injections significantly improved hair density, hair follicle density, and hair diameter in 60 patients with androgenic alopecia, with a 93% patient satisfaction rate and no reported complications over a 6-month follow-up period.
September 2021 in “CRC Press eBooks” This review discusses fibrosing alopecia in a pattern distribution and highlights diagnostic features, but reports no new clinical results; the authors emphasize the value of trichoscopy and histology in diagnosis.
October 2024 in “Skin Appendage Disorders” This study found that serum FABP4 levels were significantly higher in alopecia areata patients compared to healthy controls and may correlate with disease severity.
In this study, researchers found that FGF9 plays a significant role in sheep wool growth by accelerating the proliferation and cell cycle of dermal papilla cells, potentially through regulation of the Wnt/β-catenin signaling pathway.
5 citations
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November 2020 in “Dermatologic Therapy” This study found that a mutant form of the FGF5s protein, FGF5sC93S, significantly increased hair count after 24 weeks of application on human scalps, suggesting its potential as a hair growth treatment.
7 citations
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March 2022 in “International Journal of Molecular Sciences” This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.
21 citations
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October 2007 in “Journal of Investigative Dermatology” Fetuin-A helps wounds heal without scars by promoting cell movement.
January 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study found that the novel culture condition gHFEM, which includes Y-27632 and bFGF, optimally promotes the proliferation and pluripotency of goat hair follicle stem cells in vitro.
November 2021 in “International Journal of Trichology” This study found that trichoscopy can confirm the diagnosis and assess the clinical severity of female androgenetic alopecia, correlating specific features with different severity grades.
July 2020 in “Journal of Tissue Engineering and Reconstructive Surgery”
July 2023 in “Indian Journal of Animal Health” This study found that fibroblast growth factor 5 may enhance Cashmere goat hair growth by altering the expression of specific genes related to keratin and keratin-associated proteins.
1 citations
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August 2022 in “International Journal of Molecular Sciences” In this study, FGF12 was found to promote hair growth in mice by inducing the anagen phase of hair follicles, suggesting potential for hair loss therapy.
June 2020 in “International Journal of Women’s Dermatology” This case report highlights the importance of considering frontal fibrosing alopecia in young women, emphasizing early diagnosis to preserve hair and limit inflammation.
154 citations
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November 2017 in “Development” This review discusses the roles of fibroblast growth factors in tissue regeneration and repair across various organisms and tissues, but reports no new experimental findings, underscoring the need for further research.
2 citations
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January 2022 in “Experimental Dermatology” This paper proposes that GDNF signaling may enhance skin regeneration and hair follicle formation by influencing dermal fibroblast differentiation, particularly following injury.
June 2026 in “Annals of Medicine and Surgery” This study highlights the approval of orforglipron under the FDA's National Priority Voucher program, emphasizing its significance as a convenient oral treatment option with beneficial effects on glycemic and lipid profiles for diabetes and obesity management.
This study found that patients with frontal fibrosing alopecia showed significant alterations in protein expression in forehead corneocytes, suggesting the condition may have systemic implications beyond the scalp.
February 2026 in “International Journal of Nanomedicine” This study demonstrated that engineered exosomes carrying EGF and FGF restored hair density and follicle integrity in an androgenetic alopecia mouse model by reactivating hair follicle growth factors, offering a novel therapeutic approach without immunogenic reactions or systemic toxicity.
August 2013 in “Nature Reviews Drug Discovery” A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
1 citations
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September 2025 in “Frontiers in Veterinary Science” This study observed structural and molecular changes in Ganxi goat skin that adapt to hot and humid climates and suggested that GSDMA might play a role in hair follicle regulation and skin homeostasis, though further research is needed to confirm its function in environmental adaptation.
November 2021 in “CRC Press eBooks” This article reviews the characteristics and presentation of fibrosing alopecia in a pattern distribution, a form of scarring alopecia similar to androgenetic alopecia and lichen planopilaris, but provides no new clinical findings.
August 2025 in “Biomolecules” This review explores the role of FGF signaling in hair follicle development and highlights its potential as a new therapeutic target for hair loss, which could surpass existing treatments in terms of efficacy and safety.
4 citations
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January 2020 in “Skin appendage disorders” This case report describes a unique presentation of frontal fibrosing alopecia characterized by a hair loss pattern that resembles the Greek letter upsilon, supported by trichoscopic and histological findings.
July 2024 in “Journal of Investigative Dermatology” The Fas/FasL pathway may play a role in alopecia areata.
16 citations
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August 2015 in “Protein Expression and Purification” This study found that recombinant human FGF9 expressed in Arabidopsis thaliana oil bodies significantly promoted the proliferation of NIH/3T3 cells.
9 citations
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January 2018 in “Journal of the European Academy of Dermatology and Venereology” A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.
1 citations
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March 2023 in “Science Translational Medicine” The researchers reported that targeting glycoprotein 130's signaling site in animal models promoted tissue regeneration and reduced osteoarthritis progression through anti-inflammatory and protective effects.
5 citations
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June 2023 in “BMC genomics” This study found that a specific genetic mutation in the Fgf5 gene may contribute to the long-hair trait in Angora rabbits by reducing the binding capacity of the FGF5 protein.
March 2005 in “Journal of the American Academy of Dermatology” This study found that key amino acids lost from hair due to weathering can be successfully reintroduced through cosmetic treatments, improving hair strength and aesthetics.