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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Knowing about finasteride's sexual side effects increases reported dysfunction.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Finasteride effectively treats BPH, but needs more trials to understand potential.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.