Pseudoglucagonoma Syndrome Following Frey's Surgery: A Case Report of a Rare Presentation

    April 2024 in “ Curēus
    S D, Sukesh Gautam S, Afthab Jameela Wahab
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    TLDR Improved nutrition quickly healed the patient's skin lesions.
    Pseudoglucagonoma syndrome, characterized by necrolytic migratory erythema without a glucagon-secreting tumor, is rare and often diagnosed late. This case report describes a malnourished male patient who developed the syndrome following Frey's surgery, presenting with a progressive skin rash and diffuse hair loss over 20 days. Examination revealed multiple erythematous and eroded plaques with hyperpigmented scaly borders on various body parts. Laboratory tests indicated anemia, neutropenia, lymphocytosis, dyslipidemia, and hypoalbuminemia. The patient's skin lesions rapidly resolved with improved nutrition.
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