research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
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540-570 / 1000+ resultsresearch Dermal Lymphatic Dilation in a Mouse Model of Alopecia Areata
Mice with alopecia areata had wider lymphatic vessels in their skin.
research Intraepidermal Injections of Autologous Epidermal Cell Suspension: A New Promising Approach to Dermatological Disorders. Preliminary Study
Injecting a person's own skin cells back into their skin is a promising, safe, and affordable treatment for skin disorders.
research Autoimmune Diseases and Acquired Von Willebrand Disease in Two Cases of Progeria
Premature aging increases the risk of immune problems and autoimmune diseases.
research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
research Clinical Application of Nonantibiotic Macrolides for Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases
Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Functionalized Biomatrix for Wound Healing and Cutaneous Regeneration: Future Impactful Medical Products in Clinical Translation and Precision Medicine
The document concludes that more research is needed on making and understanding biomaterial scaffolds for wound healing.
research Novel Compound Heterozygous Variants in the CDC6 Gene in a Russian Patient with Meier-Gorlin Syndrome
A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.
research A Microfluidic Application for Mass Production of Drug-Loaded Polymeric Microspheres for a Long-Acting Injectable With IVL-DrugFluidic, a Novel Microfluidic Microsphere Manufacturing Platform Technology
IVL-DrugFluidic® can mass-produce high-quality, long-acting injectable drug microspheres, improving patient compliance and reducing side effects.
research Skin Cancer: Understanding the Transformation from Conventional to Advanced Treatment Approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research In Vivo Response of GsdmA3Dfl/+ Mice to Topically Applied Anti-Psoriatic Agents: Effects on Epidermal Thickness, as Determined by Optical Coherence Tomography and H&E Staining
Betamethasone dipropionate reduced skin thickness, fish oil increased it, and combined treatment had no significant effect.
research Skin Manifestations Associated With Systemic Diseases – Part I
The conclusion is that early diagnosis of skin signs linked to diseases like Lupus, Dermatomyositis, and Rheumatoid Arthritis is crucial to prevent serious complications.
research Single-Cell Transcriptomics Reveals a Senescence-Associated IL-6/CCR6 Axis Driving Radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
research Wnt/β-Catenin Signaling Stabilizes Hemidesmosomes in Keratinocytes
Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
research Inhaled Medicines for Targeting Non-Small Cell Lung Cancer
Inhaling medicine may reduce side effects and improve treatment for a major lung cancer type.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research Editor's Evaluation: Role of Distinct Fibroblast Lineages and Immune Cells in Dermal Repair Following UV Radiation-Induced Tissue Damage
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
research Fibroblasts: Origins, Definitions, and Functions in Health and Disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research Development of Heritable Melanoma in Transgenic Mice
The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
research Gene Therapy to Enhance Angiogenesis in Chronic Wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research A Novel In Vivo Model for Evaluating Agents That Protect Against Ultraviolet A-Induced Photoaging
Sunscreens with higher SPF and UVA filters offer the best protection against skin aging from UVA rays.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Expression of Signaling Components in Embryonic Eyelid Epithelium
Eyelid cells share signaling components but differ in pathway activity.
research Diagnosis and Management of Vascular Ehlers-Danlos Syndrome: Experience of the UK National Diagnostic Service, Sheffield
The UK's EDS National Diagnostic Service found that early diagnosis, lifestyle advice, and regular check-ups are crucial for managing vascular Ehlers-Danlos syndrome. A combination of losartan and bisoprolol can reduce vascular events, improving survival and quality of life.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research Spontaneous Lesions of Endangered Geriatric Julia Creek Dunnarts (Sminthopsis Douglasi, Archer 1979) with Emphasis on Reproductive Pathology
Geriatric Julia Creek dunnarts often suffer from reproductive and skin diseases, impacting conservation efforts.
research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research Using the Web as a Resource on Hair Loss
The article says Rogaine and Propecia can treat hair loss, warns about unreliable internet info, and advises talking to a doctor before using hair loss products.
research Study of the Thyroid Profile of Patients with Alopecia
People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.