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Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Msx2 and Foxn1 are both crucial for hair growth and health.

Inactive hair follicle stem cells help prevent skin cancer.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Low iron and vitamin D levels are linked to hair loss in women.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

K16 can partially replace K14 but causes hair loss and skin issues.

A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Mice with human skin protein K8 had more skin problems and cancer.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

TGF-β2 plays a key role in human hair growth and development.

Leptin, a hormone, is important for starting hair growth.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.