16 citations,
January 2011 in “Archives of Dermatological Research” The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
12 citations,
November 2020 in “Journal of Dermatological Science” Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
10 citations,
May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
10 citations,
May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
8 citations,
June 2020 in “The Journal of Clinical Endocrinology and Metabolism” Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.
6 citations,
January 2010 in “Springer eBooks” SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
4 citations,
May 2021 in “Lasers in Surgery and Medicine” Light therapy reduces scalp inflammation, boosts hair regrowth with Minoxidil 2%.
1 citations,
March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
1 citations,
September 2017 in “Journal of Investigative Dermatology” Backhousia citriodora leaf extract effectively reduces oily skin across different ethnic groups.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
New insights into cell communication in psoriasis suggest innovative drug treatments.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
September 2017 in “Journal of Investigative Dermatology” HIF-1A may aid hair growth, Backhousia citriodora improves skin, autologous cells stabilize hair loss, infrared thermography assesses alopecia, and a new treatment preserves hair.
September 2017 in “Journal of Investigative Dermatology” Thermal imaging is a useful non-invasive method to diagnose active inflammation in frontal fibrosing alopecia.
September 2017 in “Journal of Investigative Dermatology” The new scalp treatment preserves hair color, reduces hair loss, and maintains hair strength.
September 2017 in “Journal of Investigative Dermatology” Stabilizing HIF-1A in hair follicles may reduce oxidative stress and promote hair growth by increasing glycolysis.
September 2017 in “Journal of Investigative Dermatology” Injections of special skin cells showed potential in treating hair loss, with some participants experiencing increased hair density.
19 citations,
June 2022 in “Molecular therapy. Nucleic acids” A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.
222 citations,
August 2014 in “Cell Metabolism” Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
80 citations,
September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
61 citations,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
50 citations,
April 2010 in “Biology direct” Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
36 citations,
February 2007 in “Journal of biological chemistry/The Journal of biological chemistry” The vitamin D receptor can work without its usual activating molecule.
35 citations,
January 2017 in “Journal of Dermatological Science” Stress can cause early aging in certain skin cells, leading to problems with hair growth.
17 citations,
May 2018 in “BMC genomics” Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.
14 citations,
May 2012 in “Endocrine Research” The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
March 2024 in “Antioxidants” Excessive blue light harms eye cells and disrupts sleep patterns.
February 2024 in “Epigenomes” Epigenetic mechanisms control skin development by regulating gene expression.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
Researchers made a mouse model with curly hair and hair loss by editing a gene.