Backhousia Citriodora Leaf Extract: A New Active Solution to Control Hyper-Seborrhea for Multi-Ethnic Skins
September 2017
in “
Journal of Investigative Dermatology
”
Studysummary This research observed that Backhousia citriodora leaf extract effectively reduced sebum production and improved sebum composition across different ethnicities, significantly decreasing skin oiliness and the likelihood of shiny skin when used in a cream applied twice daily for 28 days.
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The document presents a study on the effectiveness of Backhousia citriodora leaf extract as a new active solution to control hyper-seborrhea across multiple ethnicities. Hyper-seborrhea is characterized by excessive sebum production, leading to oily and shiny skin. The study included in vitro tests and a clinical trial with 43 multi-ethnic volunteers over 28 days, applying a cream containing 2% of the extract twice daily. The in vitro results showed an 18% protection of squalene from oxidation and a 32% decrease in the protein expression of the sebocyte differentiation marker. Clinically, the extract significantly reduced skin sebum quantity by 7% across all ethnicities, with specific reductions in squalene and glycerid contents by 15% and 23% in Caucasians, 11% and 15% in Asians, and 46% and 44% in African-Americans, respectively. Additionally, the extract reduced the shiny effect of sebum on the skin by 1% in Caucasians, 3.4% in Asians, and 11% in African-Americans. The study concluded that Backhousia citriodora leaf extract effectively rebalances sebum quality and secretion by acting on oxidation, composition, and production, regardless of ethnicity, offering a new solution for oily and shiny skin.