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Licorice has many health benefits but should be used carefully due to possible side effects.

Targeting the Smoothened receptor shows promise for treating certain cancers.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Stem cells in hair follicles can become various cell types, including neurons.

L-Cysteine may have health benefits, but its effectiveness is still debated due to limited clinical trial data.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Androgens play a key role in causing PCOS (Polycystic Ovary Syndrome).

Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.

PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Gut microbes significantly affect brain steroid levels.

The true incidence of post-Finasteride syndrome is unclear, and more research is needed.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.

A special receptor in sensory nerve endings helps control how they respond to stretching.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.