2 citations
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July 2015 in “The Open Dermatology Journal” This review summarizes the main trichoscopic findings for diagnosing common hair and scalp disorders, but reports no new clinical results.
August 2024 in “STAR Protocols” This study details a step-by-step protocol for preparing mammalian skin samples, including hair follicles, for spatial transcriptomics to overcome challenges inherent in applying this technique to the skin.
March 2013 in “CRC Press eBooks” This review discusses the development and history of follicular unit transplantation and reports no new clinical results.
1 citations
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January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study provided a detailed molecular profile of Cashmere goat hair follicle development using single-cell RNA sequencing, revealing unique cell populations and conserved developmental programs compared to mouse models.
3 citations
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July 2023 in “Frontiers in Aging” This research detailed a single-cell atlas showing dynamic hair follicle stem cell states associated with the hair cycle during aging in mice, highlighting differences in chromatin landscape linked to stem cell differentiation and quiescence, and providing a foundation for future exploration of aging reversal.
October 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study demonstrates that using a K15 promoter-driven GFP labeling technique allows for the identification and characterization of epithelial stem cells in adult human hair follicles.
This study identified a 14,883 bp genomic deletion affecting the Plcd1 and Vill genes as likely responsible for the abnormal phenotype observed in snthr-1Bao mice.
1 citations
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January 2001 in “Acta Archaeologica Academiae Scientiarum Hungaricae” This review details the Follicular Unit Extraction technique for hair restoration, highlighting its advantages over traditional strip surgery, but includes no new clinical findings.
August 2018 in “Journal of Investigative Dermatology” This study found that combining optical clearing methods with light-sheet fluorescence microscopy allows detailed 3D visualization of normal and pathological human skin biopsies, revealing differences in epidermal thickness and volume.
475 citations
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October 2006 in “Proceedings of the National Academy of Sciences” This study suggests that folliculin, mutated in Birt–Hogg–Dubé syndrome, and its partner FNIP1 may play a role in energy and nutrient sensing through the AMPK and mTOR pathways.
March 2021 in “Arrow - TU Dublin (Technological University Dublin)” This study tested a folate-conjugate drug delivery system and found its cytotoxicity depends on whether the treated cells overexpress folate receptors, suggesting potential for targeted chemotherapy.
23 citations
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March 2019 in “Gene” In this study, researchers found that the evolutionary and structural features of the oFGF5 gene in sheep may influence hair follicle development and hair growth regulation.
13 citations
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June 2024 in “BMC Genomics” This study found distinct expression patterns of various transcription types during hair follicle morphogenesis, providing a foundation for understanding hair development mechanisms and aiding selective breeding for desirable wool traits in a specific breed.
November 2022 in “Research Square (Research Square)” This study identified key genes and pathways involved in the growth and development of forest musk deer hair follicles, providing insights into molecular regulation and laying groundwork for future research on related diseases.
16 citations
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September 2020 in “Animals” This study found that circRNA-1926 promotes hair follicle stem cell differentiation in cashmere goats by sponging miR-148a/b-3p to increase CDK19 expression.
70 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study reports that the TrichoScan method effectively measures hair growth parameters and detected significant improvements in hair counts and thickness in men with androgenetic alopecia after finasteride treatment.
2 citations
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January 2009 in “Human cell culture”
28 citations
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October 1992 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” In this study, Scalp Immersion Proxigraphy (SIP) was shown to produce more accurate measurements of linear hair growth rate than crude phototrichogram techniques, suggesting SIP's suitability for clinical trials monitoring hair growth.
December 2019 in “Дерматологія та венерологія” Trichoscopy is a useful tool for diagnosing hair and scalp disorders.
This research suggests that plucked hair follicles may serve as a reliable surrogate tissue for tumor biopsies in drug development, based on a mouse model linking hair and tumor pharmacodynamic responses.
This study suggests that a portable OCT system may be useful for the clinical diagnosis and evaluation of skin diseases and laser treatment outcomes.
This study reported a new method enabling the observation of the full leg regeneration process in the crustacean *Parhyale hawaiensis* over 10 days, capturing cellular resolution while minimizing photodamage, through innovative imaging techniques and computer-assisted cell tracking.
January 2024 in “Wiadomości Lekarskie” This study developed an AI-driven method for classifying cells in Follicular Lymphoma cases, achieving a 63% F1-score, precision, and recall in distinguishing centroblasts from other cell types using whole slide images at x20 resolution.
2 citations
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November 2007 in “Hair transplant forum international” This abstract introduces the concept of follicular units (FUs) in the human scalp but presents no new research findings.
53 citations
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July 2002 in “Journal of Investigative Dermatology” The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.
3 citations
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June 2021 in “Frontiers in genetics” This study found that STAT3 directly inhibited the activity of the sheep FST gene promoter, consequently reducing cell proliferation and promoting a better understanding of hair follicle development mechanisms.
1 citations
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January 2021 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that loss of the folliculin protein delays transferrin receptor recycling, leading to iron deficiency and suggesting a role in the mechanisms of Birt-Hogg-Dubé syndrome.
11 citations
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June 2016 in “Stem Cell Research” This study found that a multicolor panel of four surface markers can identify new stem cell populations in mouse hair follicles, providing insights into stem cell diversity and gene expression discrepancies during tissue culture.
November 2006 in “Dermatologic Surgery” This study concluded that while transected hair follicles can survive after transplantation in follicular unit extraction, their growth rate is unsatisfactory, and they are thinner than original follicles.
17 citations
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January 2014 in “Annals of Dermatology” This study observed that using serial sectioning and d-PAS staining improved detection of Malassezia folliculitis, notably in lesions on the trunks of male patients.