January 2015 in “Dermatology online journal” A man with total hair loss also developed a rare nail condition, likely due to autoimmune issues.
[object Object] January 2018 in “Sohag Medical Journal” Combining topical dutasteride with microneedling is more effective for hair growth than microneedling alone.
835 citations,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
185 citations,
December 2011 in “Molecular and cellular endocrinology” Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
153 citations,
March 2017 in “Endocrine” Male pattern baldness involves genetics, hormones, and needs better treatments.
98 citations,
February 2007 in “Seminars in Cell & Developmental Biology” Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
90 citations,
October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
77 citations,
March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
69 citations,
February 2002 in “International Journal of Cosmetic Science” Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.
57 citations,
February 1994 in “Experimental dermatology” Melatonin affects mouse skin and may regulate skin functions.
50 citations,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
48 citations,
February 2014 in “Fertility and Sterility” Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.
39 citations,
September 2013 in “Journal of Cosmetic Dermatology” Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
37 citations,
May 2016 in “Deutsches Arzteblatt International” Hair loss requires customized treatments based on its various causes and types.
34 citations,
August 2002 in “British Journal of Dermatology” ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.
31 citations,
May 2021 in “Journal of endocrinological investigation” APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.
30 citations,
March 2010 in “European Journal of Dermatology” Hair loss in elderly women is often caused by various factors, including hormonal changes after menopause.
29 citations,
August 2017 in “Skin appendage disorders” IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.
25 citations,
September 2015 in “Clinical Endocrinology” Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.
25 citations,
March 2012 in “Journal of oncology pharmacy practice” An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.
24 citations,
March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
23 citations,
October 2018 in “Australasian Journal of Dermatology” The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.
20 citations,
September 1978 in “International Journal of Dermatology” Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.
19 citations,
March 2008 in “Nature clinical practice endocrinology & metabolism” A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.
18 citations,
January 2001 in “Annual Reports in Medicinal Chemistry” Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
16 citations,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
[object Object] 15 citations,
September 2005 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.
14 citations,
January 2012 in “International Journal of Trichology” Hodgkin's lymphoma can show up as hair loss.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.