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PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Apoptosis is crucial for healthy skin and treating skin diseases.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Malassezia-associated dermatitis can cause itching in cats with feline paraneoplastic alopecia.

Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

HIV can cause various severe or unusual skin conditions that help indicate the presence and stage of the disease.

DHT, a testosterone byproduct, causes male pattern baldness.

Alopecia common in teens, may indicate endocrine issue, minoxidil effective treatment.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.