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In this study, a microneedle patch containing conditioned media from hypoxia-pretreated stem cells enhanced hair regeneration in an androgenetic alopecia mouse model by boosting perifollicular vascularization and hair follicle stem cell activation compared to minoxidil.

This study tested a hydrogel microneedle patch delivering T reg attractants in mice with alopecia, finding it boosted regulatory T cell numbers at the site, leading to hair regrowth without causing peripheral immunosuppression, suggesting a potential new approach for autoimmune skin disease treatment.

This chapter describes the functions and purposes of hair care cosmetics, including shampoos, hair growth promoters, and grooming products, without reporting new experimental findings.

This study found that treating secondary hair follicle stem cells from Arbas cashmere goats with 10 μg/mL quercetin for 48 hours significantly boosted cell proliferation and reduced apoptosis by activating several signaling pathways, suggesting a potential strategy to enhance cashmere production.

This review explores regenerative treatment options for non-scarring alopecia, with a focus on the potential of mesenchymal stem cells for hair regrowth, but it reports no new clinical results.

This review discusses the complex role of immune disturbances and the JAK-STAT pathway in alopecia areata, noting the success of JAK inhibitors in treatment, while highlighting ongoing debates and challenges in targeting other pathways like IL-17 and TNF-α.

Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.

This study found that conditioned medium from keratinocytes improved the hair-inductive properties of cultured dermal papilla cells, suggesting potential for enhancing hair follicle regeneration.

This review examines adipose-derived stem cells as a promising therapy for alopecia but reports no new clinical results, discussing their potential mechanisms and the challenges faced in treatment development.

This study found that restoring the skin microbiome significantly improved hair growth and skin condition in androgenic alopecia model mice by modulating the immune-inflammatory balance, highlighting the potential of bacterial-based therapies for hair loss.

In this study, researchers developed a polyphenol–amino acid nanozyme capable of controlled hydrogen peroxide delivery, which effectively activated hair follicles via oxidative stress in a mouse model, suggesting a potential non-pharmacological treatment for alopecia.

In this study, hair-follicle-associated pluripotent stem cell implantation improved functional recovery and reduced inflammation in a mouse model of intracerebral hemorrhage.

This study found that umbilical cord mesenchymal stem cell-derived exosomes improved hair growth in mice with androgenetic alopecia by promoting hair follicle stem cell stemness through the RAS/ERK pathway, suggesting a potential new treatment strategy for this condition.

This study found that hair follicle-derived mesenchymal stem cells can alleviate pyroptosis and improve ulcerative colitis symptoms in mice, suggesting potential new treatments for the condition.

This study suggests that exosomes derived from dermal papilla cells, especially those cultured in three dimensions, promote hair growth and regeneration by enhancing follicular cell activity.

In this study, 7-phloroeckol, derived from marine brown algae, was found to promote hair growth by increasing cell proliferation and hair shaft elongation in cultured human hair follicles.

In this study, researchers observed that Indian head cactus extract significantly increased the proliferation of human follicle dermal papilla cells and induced the expression of hair growth-related genes, suggesting its potential as a new therapy for promoting hair growth.

This study highlights emerging regenerative strategies, such as stem cell-derived therapies and machine learning tools, that may advance hair loss treatment beyond traditional methods by promoting follicle regeneration and offering personalized care.

This review discusses the pathobiology of chemotherapy-induced alopecia and highlights challenges in managing it, reporting no new clinical results and emphasizing the need for well-designed preclinical models to develop effective treatments.

This abstract discusses the potential of platelet-rich plasma as a promising solution for hair loss and thinning, highlighting its efficiency, safety, and reproducibility compared to traditional treatments like hair grafts.

This review discusses androgenetic alopecia and reports no clinical findings; the authors highlight a need for further research.

This review proposes a combination treatment scheme with a rotational approach for managing androgenetic alopecia, drawing on evidence for effectiveness, long-term use convenience, and patient acceptance, but presents no new clinical results.

This study suggests that increased Wnt signaling may cause melanocyte stem cell exhaustion, leading to hair graying in aged mice by promoting excessive differentiation of melanocytes.

This study found that micrografts containing human hair follicle mesenchymal stem cells significantly increased hair count and density compared to placebo over 58 weeks in patients experiencing hair loss.

This review discusses current and emerging therapeutic strategies for androgenetic alopecia, noting limited evidence but suggesting areas such as prostaglandin analogs, PRP, and progenitor cell therapies as promising future directions.

This study found that Cnidium officinale extract and its compound ferulic acid improved hair growth by promoting dermal papilla cell function and mitochondrial activity, suggesting their potential as a new treatment option for alopecia, possibly through estrogen receptor alpha activation.

This study found that Annurca apple polyphenolic extracts reprogram hair follicle metabolism in mice, enhancing mitochondrial activity and keratin production while inhibiting some metabolic pathways.

In this study, black rice extract ointment was found to enhance hair follicle growth in Wistar rats, with 10% to 30% formulations showing progressively greater hair growth after 21 days, attributed to the high antioxidant content.

In this study of patients with Androgenic Alopecia, micro-grafts containing HD-AFSCs resulted in significantly improved hair density and follicle count over 11 months compared to a saline solution, suggesting a potential alternative therapy for hair regrowth.

This study found that hair thickness and density increased after treatment with human follicle mesenchymal stem cells and platelet rich plasma, associated with enhanced Wnt signaling and platelet derived growth factors.