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Linalool in fragrances may harm hair follicles and contribute to hair loss.

The document covers various dermatological treatments and conditions.

This study observed that treating hair follicles with BM15766 and 7DHC led to structural damage, disrupted cellular organization, reduced expression of key genes and proteins, and increased apoptosis, in contrast to controls, indicating detrimental effects on hair follicle integrity.

This study found that overexpression of the FA2H gene in cashmere goats' hair follicle cells may enhance hair proliferation and regulate genes affecting cashmere fineness.

In this clinical trial, the topical agent AP-FHG0604T significantly increased hair counts and growth rates in women with female pattern hair loss compared to a placebo, though some reported mild local irritation.

This study established a sensitive and reproducible method for determining the levels of four organic solvents in finasteride raw materials, meeting the requirements of the Chinese Pharmacopeia.

This study found that ingesting Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. extract promoted hair regrowth and follicle maturation in mice by enhancing cytoprotective effects and growth factor expression.

This study found that the serine protease inhibitor ONO-3403 significantly suppressed tumor growth in mice with induced squamous cell carcinoma without apparent side effects, suggesting its potential for cancer treatment.

This study found that lncRNA-599554 contributes to the inductive ability of dermal papilla cells in cashmere goats by sponging miR-15a-5p, promoting Wnt3a expression, and potentially influencing hair follicle regeneration.

This study demonstrated that LGR5 is a marker of hair follicle stem cells across species using a transgenic pig model and noted similarities and differences in expression patterns compared to humans.

This study successfully cloned and characterized the LEF-1 gene from Inner Mongolia Cashmere Goats, potentially aiding efforts to enhance cashmere production through genetic modification.

In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.

In this study, researchers identified genetic factors associated with frontal fibrosing alopecia, noting a protective effect of a specific CYP1B1 gene variant, which may offer insights into the disease's pathogenesis and future risk mitigation strategies.

This study found that canine hair follicle stem cells in vitro expressed markers associated with multipotency, suggesting their potential role in the hair cycle.

This study generated a transcriptomic map of human hair follicle compartments, providing a database for identifying compartment-specific gene expression which may aid in developing targeted treatments for hair follicle disorders.

This study found that circRNA-0100 promotes differentiation of secondary hair follicle stem cells into hair lineage in cashmere goats by sequestering miR-153-3p, which enhances KLF5 expression.

Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.

A rare skin condition causes red and dark patches on the face and limbs.

This study identified a heterozygous de novo mutation in the ODC1 gene causing a new disorder characterized by overgrowth and developmental delay, and suggests that DFMO treatment may help manage elevated ODC activity and putrescine levels.

This study suggests that allergens like linalool found in personal care products may contribute to the pathobiology of frontal fibrosing alopecia by affecting immune responses and stem cell function in hair follicles.

This study found that fig leaf extract significantly downregulated inflammatory and androgenic gene expression in vitro, suggesting potential topical benefits for certain skin disorders.

This study established a reliable method for determining residual solvents in Finasteride using gas chromatography.

This phase I study reported that ETC-159, targeting Wnt signalling, showed tolerable safety profiles at doses that inhibit its pathway, though bone turnover markers increased, warranting early and regular monitoring. No tumor responses were observed, but two patients achieved stable disease for several cycles.

This study identified FP-1 as a highly specific extracellular matrix protein in follicular papilla cells, which may play a role in hair growth regulation during specific hair cycle phases.

This study found that ocu-miR-205 promotes the apoptosis of dermal papilla cells and the transformation of hair follicles from growth to regression and resting phases in Rex rabbits.