TLDR Canine hair follicle cells show stem cell properties, aiding hair growth.
The study investigated the multipotent stemness of canine hair follicle stem cells (cHFSCs) using Fluorescence Activated Cell Sorting (FACS) and immunostaining techniques. Canine hair follicular cells were cultured in Williams’E media with growth factors, and 18.28% of the cells were found to be positive for the CK15 marker, indicating their stemness. The positive expression of CK15, observed with DAPI counterstaining, suggested that cells in the canine hair follicular bulge region acted as precursors involved in the hair cycle.
5 citations,
December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.
27 citations,
January 2006 in “Colloids and Surfaces B: Biointerfaces” Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
March 2022 in “Indian Journal of Animal Research” Dog hair follicle stem cells can turn into fat cells.
5 citations,
December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.
36 citations,
April 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
8 citations,
July 2015 in “European journal of histochemistry” Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
1 citations,
March 2019 in “Chinese Medical Journal” Researchers identified potential markers for human hair color stem cells.
