Immunohistochemistry of Canine Hair Follicle Stem Cells Using CK15 and CK19
April 2020
in “
Journal of animal research
”
This study aimed to identify adult stem cells in canine hair follicular tissue by analyzing skin samples from 12 adult dogs. Researchers used immunohistochemistry with markers CK15 and CK19 to characterize hair follicle stem cells. They found immunoreactivity for these markers in the bulge/isthmus region of hair follicles, particularly in the peripheral layer of the outer root sheath cell. The findings confirmed the presence of canine Hair Follicle Stem Cells (cHFSCs) in the bulge region, which could be used for future in vitro culture and translational research.