September 2013 in “Neurodegenerative disease management” This review discusses teriflunomide as a disease-modifying therapy for multiple sclerosis and highlights its effectiveness and safety in clinical trials, but reports no new clinical results.
33 citations
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December 2012 in “NMR in Biomedicine” This study reports that microencapsulation of therapeutic cells with contrast agents enables visualization across multiple imaging modalities, potentially improving cellular immunoprotection and tracking after transplantation.
September 2017 in “Journal of Investigative Dermatology” QMSI effectively maps and quantifies drug distribution in skin tissues.
April 2021 in “Journal of Investigative Dermatology” This study explored the use of an AI-driven device, HairMetrix, to quantitatively assess the effects of PRP treatments on scalp health in two Caucasian women with androgenetic alopecia, reporting increases in average hair width and follicle count after one treatment.
24 citations
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September 2018 in “Lasers in Surgery and Medicine” This study shows that multiphoton microscopy can non-invasively distinguish between scarring and non-scarring alopecia by identifying certain morphological features, but further research is needed to confirm its clinical utility.
2 citations
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March 2025 in “PNAS Nexus” In this study, researchers used Raman spectroscopy to identify melanin-specific features in mouse hair as potential biomarkers for gamma-radiation exposure, achieving a sensitivity of 88% and specificity of 83%, with classification accuracy declining over time beyond 7 days post-irradiation.
31 citations
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July 2004 in “Molecular Medicine” This study found that mutant glucocorticoid receptors have defective transcriptional activity and dynamic motility issues in the nucleus, likely due to impaired interactions with nuclear molecules necessary for gene activation.
This review discusses recent advances in noninvasive hair imaging technologies, such as global photography, trichoscopy, reflectance confocal microscopy, and optical coherence tomography, highlighting their potential to improve hair diagnostics and treatment monitoring, while also outlining their clinical applications and limitations.
2 citations
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December 2008 in “Clinical and Experimental Dermatology” This case report describes a 10-year-old girl with a cosmetically concerning forehead lesion and a history of right frontal headaches, featuring a small palpable and pulsatile erythematous lesion with associated macular erythema.
August 1994 in “Journal of Dermatological Science”
November 2023 in “Research Square (Research Square)” This animal study found that finasteride, a 5-alpha reductase type 2 inhibitor, decreased dihydrotestosterone levels and c-Fos protein activation in the rat brain, but these effects may diminish after discontinuing the drug.
22 citations
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November 2020 in “Frontiers in Physics” This review discusses the experimental strategies and technological challenges of proton minibeam radiotherapy (pMBRT) and reports no clinical results; it highlights the potential of using a 3 GHz linear accelerator for precision therapy research.
4 citations
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May 2011 in “Movement Disorders” A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.
May 2023 in “Experimental Dermatology” This study found that both reflectance confocal microscopy and optical coherence tomography can visualize detailed hair follicle abnormalities in various skin disorders, but larger, higher-quality studies are needed for clinical implementation.
This study explored using 3D models derived from reflectance confocal microscopy to better understand and differentiate melanoma on sun-damaged skin, suggesting enhanced diagnostic possibilities.
28 citations
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December 2002 in “Der Hautarzt” TrichoScan accurately measures hair growth and loss, showing increased hair counts and thickness with treatment.
5 citations
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January 1995 in “Journal of Investigative Dermatology” A trial found that using finasteride, a hair growth drug, can be effectively measured by comparing before and after photos.
36 citations
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March 2002 in “Journal of Biological Chemistry” Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
1 citations
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January 2018 in “Medical Science and Discovery” This review examines the characteristics of frontal fibrosing alopecia in postmenopausal women, highlighting the importance of biopsy for early diagnosis and potential treatment to prevent disease progression.
5 citations
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May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.
August 2013 in “Fertility and sterility” This study suggests that metformin might serve as a diagnostic and therapeutic option to distinguish insulin resistance-related ovarian testosterone excess from a testosterone-secreting tumor in women with virilization.
4 citations
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February 2020 in “Cell & tissue research/Cell and tissue research” This study suggests that adult hair follicle stem cells can survive and potentially differentiate into neuronal cells after being transplanted in a mouse model of traumatic brain injury, indicating promise for TBI therapy.
14 citations
,
February 2003 in “Journal of the American Academy of Dermatology” This case report describes the first use of laser capture microdissection to confirm that atypical lymphocytes in a folliculotropic mycosis fungoides case involving the central nervous system were part of the same tumor clone.
December 2025 in “BMC Medical Genomics” This study demonstrated that RNA-seq can effectively expand hair follicle transcriptomic profiling in a multi-center study, offering deeper insights than blood transcriptomics alone.
25 citations
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March 2002 in “Scanning” This study highlights confocal microscopy as a promising, minimally invasive tool for assessing hair morphology and internal structures, making it valuable for cosmetic hair assessments.
July 2011 in “F1000Research” 13 citations
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June 2014 in “Molecular therapy” This study found that a lentiviral array of reporters can identify lineage-specific promoters and pathways in mesenchymal stem cell differentiation, aiding in the prediction of signaling pathway effects.
September 2015 in “Dermatologic Surgery” In this study, the researchers developed a computer-aided imaging system to quantitatively measure baldness in Chinese women with female pattern hair loss, potentially improving the precision of severity evaluation compared to traditional scales.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study revealed distinct cellular and transcriptomic differences among various subtypes of cutaneous T-cell lymphoma, particularly highlighting characteristics unique to folliculotropic mycosis fungoides.