Reproducibility of Global Photographic Assessments of Patients With Male Pattern Baldness in a Clinical Trial With Finasteride

    January 1995 in “ Journal of Investigative Dermatology ”
    Kenton R. Kaufman, Bruce Binkowitz, Roxana Savin, Donald E. Canfield
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    TLDR A trial found that using finasteride, a hair growth drug, can be effectively measured by comparing before and after photos.
    In 1994, a 12-month, randomized, placebo-controlled, multicenter pilot clinical trial was conducted to study the effects of oral finasteride, a 5α-reductase inhibitor, on men aged 18 to 35 years old with Hamilton classification III vertex or IV male pattern baldness (MPB). The study used various clinical efficacy endpoints including hair counts, patient self-assessment, investigator assessment, and blinded assessment of global photographic slides of the vertex area. The validity of the global photographic assessment was tested for reproducibility by a single experienced dermatologist who rated each patient's change from baseline in hair growth at the end of the 12-month study period. The results of this study were not provided in the document.
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