April 2005 in “World Journal of Pharmaceutical and life sciences” This article discusses the formulation and evaluation of hair gels that may improve the treatment and prevention of dandruff by providing longer-lasting effects compared to traditional shampoos and lotions, but it reports no new clinical findings.
1 citations
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July 2013 in “Clinical Drug Investigation”
November 2020 in “Skin Research and Technology” This study found that videodermoscopy showed higher sensitivity and specificity than clinical examination for diagnosing female pattern hair loss and may serve as an alternative to scalp biopsy in the future.
April 2025 in “Journal of Reproductive Healthcare and Medicine” This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.
6 citations
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July 2013 in “Molecular Imaging” This study successfully used noninvasive bioluminescence imaging to monitor hair generation in vivo after transplanting hair follicle stem cells in mice.
1 citations
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July 2025 in “Frontiers in Genetics” In this study, researchers classified melanomas by filaggrin expression levels and found that in filaggrinHigh melanomas, there are significant changes in FGFR signaling and impaired GNA14 and Th1 signatures, linked to genetic and immune alterations associated with pruritus.
March 2024 in “Current materials science” This study explores the various properties of the flavonoid fisetin, highlighting its potential therapeutic applications due to its ability to modulate numerous biological pathways, suggesting benefits in conditions like inflammation, cancer, and neurodegenerative diseases.
June 2025 in “Healthy-Mu Journal” The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
31 citations
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September 2011 in “European journal of pharmaceutics and biopharmaceutics” This study found that biodegradable PLA particles released fluorochromes in a time-dependent manner on human skin, with BP-PLA particles releasing rapidly and DiAsp-PLA particles providing sustained release and accumulation in hair follicles.
April 2017 in “DR-NTU (Nanyang Technological University)” This study found that adjusting the polymer gel composition can create a more consistent release profile of finasteride with reduced initial burst release, enhancing patient compliance through in situ polymer precipitation.
3 citations
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November 2017 in “International Journal of Pharmacy and Pharmaceutical Sciences” This study identified new oxidative derivatives of finasteride, including a newly discovered metabolite, by using the fungus Macrophomina phaseolina.
3 citations
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December 2021 in “Materials today communications” This study found that a keratin film made from human hair supports enhanced cell proliferation and viability compared to collagen I, suggesting potential for cell culture applications.
30 citations
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November 1992 in “The Journal of Dermatology” This review discusses the roles of filaggrin and trichohyalin in keratinocyte differentiation and reports no new results; the authors introduce possible hybrid granules in tongue epithelia.
2 citations
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June 2025 in “ACS Biomaterials Science & Engineering” This study demonstrates that encapsulating cell-free fat extract in a gelatin methacrylate hydrogel enhances flap repair by sustaining angiogenesis, reducing oxidative stress, and offering favorable biocompatibility in a murine skin flap model, thereby advancing potential clinical flap necrosis treatments.
1 citations
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January 2021 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that loss of the folliculin protein delays transferrin receptor recycling, leading to iron deficiency and suggesting a role in the mechanisms of Birt-Hogg-Dubé syndrome.
5 citations
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December 2015 in “PubMed” This study identified several gonadal hormone drugs, including toremifene citrate, tamoxifen citrate, and clomiphene citrate, that effectively inhibited filovirus entry in a pseudovirus model.
October 2022 in “Regenerative Biomaterials” This study demonstrated that fibrin hydrogels support skin-derived precursors in hair follicle neogenesis in mice, with new hair growth and regeneration of blood vessels and sebaceous glands observed.
9 citations
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January 1999 in “Journal of Liquid Chromatography & Related Technologies” This article discusses using high performance liquid chromatography to optimize mobile phase composition for separating synthesis products of Finasteride, without reporting new clinical results.
April 2018 in “Journal of Investigative Dermatology” This study suggests that weekly oral finasteride may be a promising alternative to isotretinoin for treating nodulocystic acne, showing substantial improvements with lower incidence of sexual dysfunction.
2 citations
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February 2021 in “European Journal of Plastic Surgery” This study found that the Fibonacci 'snail' flap for scalp defect reconstruction healed faster and resulted in better aesthetic outcomes than skin grafts, though not all complication rate differences were statistically significant.
March 1998 in “Dermatologic Surgery” In this study, miniflap scalp reconstruction with a staged scalp-lifting procedure showed excellent flap viability, acceptable scarring, and customizable hair direction, offering a preferred option for hair relocation in selected cases.
In this study, researchers developed de novo designed hetero-bifunctional proteins as an alternative approach for targeted protein degradation, successfully targeting BCL-xL for degradation in cells and inducing apoptosis, which may expand the range of addressable E3 ligases and disease targets.
May 2026 in “Cell Reports Medicine” This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.
1 citations
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March 2010 in “International Journal of Cosmetic Science” This study introduces a new device for measuring changes in hair stiffness and lubricity, which can help predict the effects of various hair treatments.
47 citations
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September 2013 in “Aaps Pharmscitech” This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.