November 2024 in “Journal of Microscopy” This study found that micro-computed tomography (micro-CT) was highly effective for analyzing the cross-sectional geometry of hair fibres, including the medulla in highly curled hair, but less effective than scanning electron microscopy for surface details.
September 2024 in “Journal of Investigative Dermatology” This study developed a deep learning-based tool to quantify individual hair fibers in mice, revealing distinct hair phenotypes linked to hormonal, genetic, and age-related factors, and suggesting its potential for new diagnostic methods through hair analysis.
April 2024 in “Journal of Investigative Dermatology” This study identified three new genetic loci linked to sweat gland density in a GWAS involving 6,210 Han Chinese individuals, highlighting potential targets for understanding conditions like anhidrosis and hyperhidrosis and emphasizing the use of quantitative traits in genetic dermatology research.
April 2024 in “International journal of molecular sciences” This review examined and discussed the role of dermis-derived factors in the regulation of melanogenesis, noting their significance in both normal and abnormal mammalian skin conditions, suggesting an underexplored area of study compared to dermal and epidermal influences.
This study investigated the expression of KRTAP6 gene family in Gansu Alpine fine-wool sheep, finding significant expression during the anagen phase and a negative correlation between KRTAP6-1 and KRTAP6-5 expressions with wool fiber diameter and strength.
October 2023 in “International journal of women’s dermatology” This study observed that while hair camouflage techniques can boost confidence and reduce stigma for Black women with alopecia, they can also contribute to further hair damage; clinicians should consider safer styling practices as part of individualized care strategies.
This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.
April 2021 in “Indian Journal of Animal Research” This study examined the age-related changes in the dermal structure of goat skin, providing baseline data on its histomorphology, histochemistry, and histoenzymology.
April 2023 in “Chinese Medical Journal” In this study, human hair follicle-derived mesenchymal stem cells promoted Achilles tendon repair in rabbits by upregulating collagen types I and III, suggesting potential as a treatment for tendinopathy.
October 2025 in “International Wound Journal” In a study using a rat model of hypertrophic scars, researchers found that gamma-irradiated human amniotic fluid improved wound healing, collagen remodelling, immune response, and scar characteristics more effectively than saline or non-irradiated amniotic fluid, indicating its potential for clinical applications in scar management.
149 citations
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June 2010 in “The FASEB journal” In this study, miR-31 was found to play a significant role in hair cycle regulation in mice by controlling key gene expressions involved in hair growth and differentiation.
51 citations
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October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
48 citations
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May 2021 in “Molecules” The researchers found that plant extracts from Papaver rhoeas L., Clitoria ternatea L., and Carthamus tinctorius L. are effective natural cosmetic dyes, offering intense and stable colors without cytotoxicity.
32 citations
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April 2020 in “BMC Developmental Biology” This study found that ocu-miR-205 influences hair follicle density and signaling pathways in Rex rabbits by promoting dermal papilla cell apoptosis and altering hair follicle phases.
15 citations
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February 2000 in “Journal of Cutaneous Pathology” This study suggests that the anchorage of the arrector pili muscle to the extracellular matrix is likely mediated by α5β1 integrin, with α1β1 integrin involved in muscle cell-cell adhesion.
10 citations
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October 2021 in “Animal nutrition” This study found that dietary pyridoxine increased hair follicle density in Rex rabbits by activating PI3K/Akt, Wnt, and Notch signaling pathways, which may promote hair growth and delay telogen onset.
7 citations
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November 2006 in “Journal of immunological methods” This study found that the novel dot-block method can effectively measure early- and advanced-glycation products in hair, suggesting its potential for monitoring diabetes progression and other chronic conditions.
3 citations
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January 2025 in “International Journal of Molecular Sciences” In this study, researchers investigated EGCG's spectroscopic properties and its interaction with DPPG lipid, finding that both experimental and theoretical approaches agree on the electronic transitions and reveal an increased absorbance due to molecular interactions.
March 2026 in “Scientific Data” This study mapped the genome-wide epigenetic landscape in secondary hair follicle stem cells of goats, revealing distinct histone modification signatures associated with cashmere fiber cycling during different stages of hair growth.
February 2024 in “Journal of Cellular and Molecular Medicine” In this study using rat models, researchers developed a Pluronic@F-127 hydrogel to deliver the flavonoid pectolinarin, finding it accelerates wound healing and reduces scar formation by enhancing cell migration, proliferation, and antioxidant activity.
November 2022 in “Scientific Reports” This study found that ESR1 gene polymorphisms may be linked to hormonal imbalances in young women with hyperandrogenism, potentially affecting bone mineral density indirectly.
August 2022 in “International Journal of Molecular Sciences” This study found that lncRNA2919 negatively impacts hair follicle regeneration by decreasing follicle depth and density in a rabbit model, suggesting a regulatory role in the hair follicle cycle through DNA methylation.
24 citations
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March 2008 in “Neuroscience Research” This study revealed the complex three-dimensional innervation of touch domes in cat forepaw skin, highlighting the extensive branching and unmyelinated endings associated with Merkel cell–axon complexes.
2 citations
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January 2015 in “Sen'i Gakkaishi” This study found that washing hair after reduction in a permanent waving process allows for significant reformation of disulfide cross-links, enhancing the strength and elasticity of hair fibers.
August 2025 in “Biomacromolecules” This study presents a novel composite hydrogel dressing with berberine-loaded silk fibroin microspheres and Calotropis gigantea fibers, demonstrating enhanced antibacterial activity, mechanical strength, and wound healing capabilities in treating chronic and infected wounds.
January 2025 in “Diagnostics” In this prospective case-control study, researchers found that women with any phenotype of polycystic ovary syndrome exhibited increased retinal nerve fiber layer and choroidal thickness compared to healthy controls, with changes correlated to body mass index.
April 2017 in “Journal of dermatology & cosmetology” In this controlled study, a 6-month treatment with the nutraceutical product ViviScal® reduced telogen hair fibers and increased total hair fibers in 83% of participants with Telogen Effluvium, who also reported improved hair and nail growth, skin appearance, and overall quality of life.
61 citations
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October 1996 in “Development” This study found that combining adult germinative epidermal cells with non-inductive dermal cells can stimulate hair follicle neogenesis, effectively altering the cells' status to enhance induction.
31 citations
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January 2019 in “Journal of Cutaneous Medicine and Surgery” This review found that three monthly PRP injections improved hair density in patients with androgenetic alopecia compared to placebo, but more rigorous studies are needed for broader dermatological applications.
October 2025 in “Folia Morphologica” This study found that lymph vessel morphology and density in airways differed based on location and type of epithelium, with the highest density in the ciliated epithelium of the nasal passages and site-specific patterns apparent in both fetal and adult specimens.