Evaluation of Retinal Changes in Women with Different Phenotypes of Polycystic Ovary Syndrome

    January 2025 in “ Diagnostics ”
    Fatma Sümer, Beril Gürlek, Elif Yıldız, Feyzahan Ekici, Sabri Çolak, İlknur Merve Ayazoğlu
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    TLDR Women with PCOS have distinct retinal changes compared to healthy women.
    This study evaluated retinal changes in 150 women, including 120 with different phenotypes of polycystic ovary syndrome (PCOS) and 30 healthy controls. It found that women with PCOS had significantly greater retinal nerve fiber layer (RNFL) and choroidal thickness compared to controls, particularly in the nasal quadrants, while the temporal inner and outer macula and central macula were thinner. The study also noted a positive correlation between body mass index (BMI) and changes in choroidal thickness. These findings suggest that PCOS phenotypes are associated with distinct retinal alterations, potentially linked to hormonal changes, and highlight the need for further research to explore the long-term effects of PCOS on ocular health.
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