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PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Hirsutism causes significant psychological distress in women.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Sex steroids affect the MafB gene differently in male and female hamsters.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

Testosterone is crucial for development, growth, and various body functions in mammals.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

PPAR alpha may help in hair growth and could be a target for treatment.

Antiandrogen therapy helps treat genetic hair loss.

Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.

Skin health and diseases are closely linked to metabolic processes.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Minoxidil can reduce functions related to androgen receptors.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

Vitamin D3 may protect rat hair follicles from radiation damage.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

Men with frontal male pattern baldness may have a higher risk of gastric cancer.