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This pilot study suggests that high-dose testosterone plus finasteride improved body composition in men with impaired gait and low to low-normal testosterone after chronic incomplete spinal cord injury.

This study found that GTx-024 significantly increased total lean body mass and improved physical function in healthy elderly men and postmenopausal women, suggesting potential use for muscle wasting conditions.

This study outlines a method to isolate hair follicle stem cells from mouse skin using fluorescence activated cell-sorting for use in research models, but reports no experimental findings.

This study is the first to report major spontaneous diseases in aging Julia Creek dunnarts, highlighting hormonal dysregulation and lymphoid neoplasia as common conditions in this endangered species.

This case study highlights Erythromelanosis follicularis faciei et colli as an easily overlooked pigmentary disorder characterized by a distinctive triad requiring precise diagnosis for effective patient counseling and cosmetic management.

This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.

This study highlights the potential of cosmetic products combining fibroblast growth factors and antioxidants like thioproline, ergothioneine, silymarin, and rosmarinic acid, to mitigate skin aging by reducing oxidative stress and enhancing cellular protection in the skin.

This review discusses various mechanical isolation procedures for tissue-like stromal vascular fraction, such as the nanofat procedure, and highlights the need for controlled trials to assess their regenerative effectiveness.

This study found that CRISPR/Cas9-induced loss-of-function mutations in the FGF5 gene significantly increased wool length and yield in genetically modified Chinese Merino sheep compared to wild-type controls.

This study found that finasteride improved cardiac function and reduced remodeling after myocardial infarction in mice.

This article discusses finasteride's use for male pattern alopecia and highlights the positive experiences and observations by hair restoration surgeons but reports no new clinical results.

In this study, researchers reported significant improvement in sexual function and related symptoms for four patients using off-label flibanserin, suggesting potential broader applications beyond premenopausal women with hypoactive sexual desire disorder.

In this study, finasteride altered the expression of nine proteins in the rat nucleus accumbens, suggesting new therapeutic targets and mechanisms for its effects on neuropsychiatric conditions.

This study found that finasteride use was associated with significantly higher odds of obstructive sleep apnea and insomnia compared to other medications.

This study found that combined loss of Atr and p53 in adult mice led to severe tissue degeneration and delayed regeneration due to the accumulation of highly damaged cells.

This study found that repeated finasteride administration in male Wistar rats led to increased depression-like behavior, suggesting an animal model for investigating finasteride's neuropsychiatric effects is viable.

This study generated FGF5-knockout Dorper sheep using the CRISPR/Cas9 system, resulting in significantly increased fine-wool and active hair-follicle density, and explored downstream signaling pathways for potential applications in androgen alopecia treatment.

This study found that fibronectin nanofiber dressings, made using rotary jet spinning, accelerated wound healing and improved tissue restoration in a full-thickness wound mouse model.

This study describes a novel hairless mutant rat strain, F344-Hr(krh), developed via ENU mutagenesis, which provides a model for skin disease and potentially focal glomerulosclerosis due to specific genetic mutations.

In this review, cosmetic practices such as non-ablative lasers, autologous fat injections, and oral isotretinoin may help alleviate certain symptoms of frontal fibrosing alopecia, while treatments like deep chemical peels and ablative laser therapies are contraindicated due to potential scarring risks.

The study found that aging in hair follicle stem cells leads to hair follicle miniaturization and eventual hair loss in both wild-type mice and humans by proteolyzing type XVII collagen.

This study found that perinatal androgen deprivation in male rats increased serum estrogen levels and enhanced exploratory behavior, indicating that elevated estrogen may affect brain sex differentiation and related behaviors.

This study found that papillary dermal fibroblast progenitors in newborn mouse skin can be isolated and cultured to generate male germline cell precursors, demonstrating their potential through differentiation into cells with meiotic capability.

This study found that an acellular dermal matrix derived from tilapia skin significantly accelerated wound healing and improved tissue regeneration quality in mouse and pig models compared to a commercial porcine-derived matrix, suggesting its potential as a safe, cost-effective bioscaffold for skin repair.

A new method was developed to create better skin models for healing and reconstruction.

This study observed that frontal fibrosing alopecia predominantly affects postmenopausal women, can be associated with lichen planus, and may lead to progressive hairline recession, though this progression is not consistent in all cases.

This study suggests that Flightless I may inhibit the activation of epidermal stem cells during wound repair by disrupting Wnt/β-catenin signaling, potentially delaying wound reepithelialization.

This study reports that in aged mice, hair follicle dermal stem cells exhibit diminished self-renewal and preferential differentiation into dermal sheath cells, contributing to age-related hair loss.