73 citations,
June 2008 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.
67 citations,
February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
19 citations,
January 2015 in “Indian Journal of Dermatology” Skin changes in women with PCOS are mainly due to hormonal imbalances.
14 citations,
August 2014 in “Applied Physiology, Nutrition, and Metabolism” A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.
6 citations,
December 2022 in “Frontiers in Pharmacology” Quercetin may help improve symptoms of polycystic ovary syndrome.
90 citations,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.
January 2022 in “International journal of zoological investigations” Polycystic Ovarian Syndrome is common in overweight urban college girls and may increase the risk of heart and metabolic problems.
October 2022 in “The Egyptian Journal of Hospital Medicine” Females with idiopathic hirsutism have higher levels of omentin-1, which may lead to excessive hair growth.
August 2022 in “International journal of reproduction, contraception, obstetrics and gynecology” The study found that 7.21% of young girls have polycystic ovarian syndrome, with symptoms like irregular periods, abnormal hair growth, and acne. Early diagnosis is important to prevent long-term complications.
3 citations,
January 2020 in “Indian Dermatology Online Journal” Skin problems in patients with polycystic ovarian disease are linked to body weight, blood sugar, and hormone levels.
2 citations,
February 2021 in “Endocrinology, diabetes & metabolism case reports” A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.
28 citations,
February 2011 in “Clinical Endocrinology” Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.
January 2023 in “International journal of medical science and health research” Anovulatory PCOS patients are younger with longer cycles and higher blood pressure and hormone levels.
April 2018 in “International journal of innovative research in medical science” Neem and Zanjabeel are as effective as standard drugs for treating hirsutism in PCOD patients.
17 citations,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.
26 citations,
August 2014 in “Genetic Testing and Molecular Biomarkers” High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.
August 2013 in “Fertility and sterility” Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.
2 citations,
July 2012 in “Journal of Pediatric and Adolescent Gynecology” A 12-year-old girl with very high testosterone and insulin resistance improved with birth control pills, suggesting PCOS can cause high testosterone without tumors.
18 citations,
May 2017 in “Fertility Research and Practice” Larger ovarian size is linked to higher insulin resistance in women with PCOS.
26 citations,
June 2014 in “Fertility and Sterility” Teens with PCOS and a mom with PCOS have higher insulin resistance and lower adiponectin levels, which could signal early metabolic problems.
16 citations,
January 2012 in “European Journal of Endocrinology” The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.
10 citations,
October 2014 in “Journal of Ovarian Research” The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.
6 citations,
January 2018 in “Dermato-endocrinology” Darkened knuckles can be an early sign of insulin resistance.
February 2010 in “Journal of The American Academy of Dermatology” White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.
28 citations,
March 2009 in “Clinical and Experimental Dermatology” There is no significant link between male pattern baldness and insulin resistance.
22 citations,
September 2015 in “Fertility and Sterility” The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.
October 2023 in “Benha Journal of Applied Sciences” Insulin resistance may contribute to hair loss in people with androgenic alopecia.
31 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
11 citations,
September 2012 in “Journal of obstetrics and gynaecology Canada” Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
April 2019 in “Journal of the Endocrine Society” A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.