Correlation of Cutaneous Manifestations with Body Mass Index, Blood Glucose, and Hormonal Levels in Patients with Polycystic Ovarian Disease

    January 2020 in “ Indian Dermatology Online Journal
    Yugal K Sharma, Surbhi Chauhan, Pallavi Singh, Kirti Deo
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    TLDR Skin problems in patients with polycystic ovarian disease are linked to body weight, blood sugar, and hormone levels.
    In 2020, a study involving 102 non-pregnant patients with Polycystic Ovarian Disease (PCOD) aged 12-45 years found a significant correlation between cutaneous manifestations, including hair loss, and body mass index (BMI), blood glucose, and hormonal levels. The most common skin conditions observed were acne (74.50%), acanthosis nigricans (50%), and hirsutism (40.19%). The study found that acanthosis nigricans was significantly correlated with free testosterone, dehydroepiandrosterone sulfate (DHEAS), fasting blood sugar, and BMI, while hirsutism was significantly associated with elevated DHEAS, free testosterone, and BMI. However, the study had limitations such as its small size and lack of screening for fasting free insulin levels and components of metabolic syndrome.
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