Correlation of Cutaneous Manifestations with Body Mass Index, Blood Glucose, and Hormonal Levels in Patients with Polycystic Ovarian Disease

January 2020 in “ Indian Dermatology Online Journal ”

Yugal K Sharma, Surbhi Chauhan, Pallavi Singh, Kirti Deo

hair loss acne acanthosis nigricans hirsutism free testosterone dehydroepiandrosterone sulfate DHEAS fasting blood sugar BMI polycystic ovarian disease PCOD testosterone DHEA blood sugar body mass index polycystic ovary syndrome PCOS

Studysummary In this study, significant correlations were observed between acanthosis nigricans and factors like free testosterone, DHEAS, fasting blood sugar, and BMI, as well as between hirsutism and elevated DHEAS, free testosterone, and BMI among patients with polycystic ovarian disease. Our plain-language summary of this paper — not a Tressless recommendation.

In 2020, a study involving 102 non-pregnant patients with Polycystic Ovarian Disease (PCOD) aged 12-45 years found a significant correlation between cutaneous manifestations, including hair loss, and body mass index (BMI), blood glucose, and hormonal levels. The most common skin conditions observed were acne (74.50%), acanthosis nigricans (50%), and hirsutism (40.19%). The study found that acanthosis nigricans was significantly correlated with free testosterone, dehydroepiandrosterone sulfate (DHEAS), fasting blood sugar, and BMI, while hirsutism was significantly associated with elevated DHEAS, free testosterone, and BMI. However, the study had limitations such as its small size and lack of screening for fasting free insulin levels and components of metabolic syndrome.

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research Cutaneous Manifestations of Polycystic Ovary Syndrome: A Cross-Sectional Clinical Study

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In this study, skin manifestations such as hirsutism and acne were prevalent among women with PCOS, highlighting their importance in diagnosis and symptomatology.

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This meta-analysis found that the prevalence of PCOS among Iranian women varies by diagnostic criteria, with notable rates of associated complications like hirsutism, acne, and menstrual disorders.

research Correlation of Skin Changes With Hormonal Changes in Polycystic Ovarian Syndrome: A Cross-Sectional Clinical Study

19 citations , January 2015 in “Indian Journal of Dermatology”

In this study, researchers observed that 90% of patients with PCOS had cutaneous manifestations, with acne most common, and found associations between these skin conditions and high insulin or testosterone levels.

research Polycystic Ovary Syndrome: Dermatological Approach

26 citations , February 2011 in “Anais Brasileiros De Dermatologia”

This review discusses the pathophysiology, diagnosis, and treatment of polycystic ovary syndrome, emphasizing the critical importance of early diagnosis and treatment to prevent metabolic complications and improve quality of life.

Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

1744 citations , August 2006 in “The Journal of Clinical Endocrinology and Metabolism”

This review discusses definitions of polycystic ovary syndrome and reports no new clinical results; the authors support using modified 1990 NIH criteria and acknowledge ongoing evolution as research advances.

research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS)

4025 citations , December 2003 in “Human Reproduction”

This review discusses the evolution of diagnostic criteria for polycystic ovary syndrome and emphasizes its association with various metabolic and cardiovascular risks, but it provides no new research findings.